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MedKoo Cat#: 464561 | Name: Syringaldehyde
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Syringaldehyde is a polyphenol that has been found in E. granulatus and has diverse biological activities. It inhibits LPS-induced COX-2 activity in RAW 264.7 cells with an IC50 value of 19.23 µM. Syringaldehyde inhibits the proliferation of HCT116, Caco-2, and HT-29 colon cancer cells (IC50s = 56.3, 35.9, and 68.6 µM, respectively). It decreases plasma glucose levels in a rat model of diabetes induced by streptozotocin (STZ) when administered at doses ranging from 1.8 to 7.2 mg/kg. Syringaldehyde (25 and 50 mg/kg) reduces infarct size in a rat model of myocardial infarction induced by isoproterenol.

Chemical Structure

Syringaldehyde
Syringaldehyde
CAS#134-96-3

Theoretical Analysis

MedKoo Cat#: 464561

Name: Syringaldehyde

CAS#: 134-96-3

Chemical Formula: C9H10O4

Exact Mass: 182.0579

Molecular Weight: 182.18

Elemental Analysis: C, 59.34; H, 5.53; O, 35.13

Price and Availability

Size Price Availability Quantity
10g USD 250.00 2 Weeks
50g USD 450.00 2 Weeks
100g USD 750.00 2 Weeks
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Related CAS #
No Data
Synonym
Syringaldehyde; NSC 41153; NSC41153; NSC-41153; SM 707; SM707; SM-707; VND 3207; VND-3207; VND3207;
IUPAC/Chemical Name
4-hydroxy-3,5-dimethoxybenzaldehyde
InChi Key
KCDXJAYRVLXPFO-UHFFFAOYSA-N
InChi Code
InChI=1S/C9H10O4/c1-12-7-3-6(5-10)4-8(13-2)9(7)11/h3-5,11H,1-2H3
SMILES Code
O=CC1=CC(OC)=C(O)C(OC)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Solvent mg/mL mM
Solubility
DMF 30.0 164.00
DMSO 30.0 164.00
DMSO:PBS (pH 7.2) (1:7) 0.1 0.66
Ethanol 1.0 5.50
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 182.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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Food Chem. 2024 Dec 1;460(Pt 2):140332. doi: 10.1016/j.foodchem.2024.140332. Epub 2024 Jul 3. PMID: 39106805. 8: Ding B, Jiang L, Zhang N, Zhou L, Luo H, Wang H, Chen X, Gao Y, Zhao Z, Wang C, Wang Z, Guo Z, Wang Y. Santalum album L. alleviates cardiac function injury in heart failure by synergistically inhibiting inflammation, oxidative stress and apoptosis through multiple components. Chin Med. 2024 Jul 15;19(1):98. doi: 10.1186/s13020-024-00968-0. PMID: 39010069; PMCID: PMC11251102. 9: Watumlawar EC, Park BD. A Novel Method of Self-Cross-Linking of Syringaldehyde with Activated Methoxy Groups via Cross-Coupling for Lignin-Based Wood Adhesives. ACS Omega. 2024 Jun 20;9(26):28167-28175. doi: 10.1021/acsomega.4c01267. PMID: 38973923; PMCID: PMC11223239. 10: Fotakis C, Andreou V, Christodouleas DC, Zervou M. The Metabolic and Antioxidant Activity Profiles of Aged Greek Grape Marc Spirits. Foods. 2024 May 26;13(11):1664. doi: 10.3390/foods13111664. PMID: 38890893; PMCID: PMC11172063. 11: Ahmed ME, Mohamed MI, Ahmed HY, Elaasser MM, Kandile NG. Fabrication and characterization of unique sustain modified chitosan nanoparticles for biomedical applications. Sci Rep. 2024 Jun 15;14(1):13869. doi: 10.1038/s41598-024-64017-4. PMID: 38879643; PMCID: PMC11180141. 12: Silva JP, Frederico TD, Ticona ARP, Pinto OHB, Williams TCR, Krüger RH, Noronha EF. Insights on kraft lignin degradation in an anaerobic environment. Enzyme Microb Technol. 2024 Sep;179:110468. doi: 10.1016/j.enzmictec.2024.110468. Epub 2024 Jun 3. PMID: 38850683. 13: Leitão MM, Vieira TF, Sousa SF, Borges F, Simões M, Borges A. Dual action of benzaldehydes: Inhibiting quorum sensing and enhancing antibiotic efficacy for controlling Pseudomonas aeruginosa biofilms. Microb Pathog. 2024 Jun;191:106663. doi: 10.1016/j.micpath.2024.106663. Epub 2024 Apr 26. PMID: 38679246. 14: Lee J, Li Y, Cheng JT, Liu IM, Cheng KC. 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S 1688