IUPAC/Chemical Name
Cyclohexanecarboxylic acid, 2-(((2-(hydroxyamino)-2-oxoethyl)methylamino)carbonyl)-, (1S-cis)-
InChi Key
QKIVRALZQSUWHH-SFYZADRCSA-N
InChi Code
InChI=1S/C11H18N2O5/c1-13(6-9(14)12-18)10(15)7-4-2-3-5-8(7)11(16)17/h7-8,18H,2-6H2,1H3,(H,12,14)(H,16,17)/t7-,8+/m1/s1
SMILES Code
CN(CC(=O)NO)C(=O)[C@@H]1CCCC[C@@H]1C(=O)O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
258.27
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1. Taddei S, Ghiadoni L, Mattei P, Sudano I, Duranti P, Favilla S, Virdis A, Romagnoli A, Criscuoli M, Coppini A, et al. Humoral and haemodynamic effects of idrapril calcium, the prototype of a new class of ACE-inhibitors, in essential hypertensive patients. Eur J Clin Pharmacol. 1995;48(5):339-43. doi: 10.1007/BF00194948. PMID: 8641320.
2. Subissi A, Criscuoli M, Sardelli G, Guelfi M, Giachetti A. Pharmacology of idrapril: a new class of angiotensin converting enzyme inhibitors. J Cardiovasc Pharmacol. 1992 Jul;20(1):139-46. PMID: 1383623.
3. Zanchi A, Nussberger J, Criscuoli M, Capone P, Brunner HR. Angiotensin-converting enzyme inhibition by hydroxamic zinc-binding idrapril in humans. J Cardiovasc Pharmacol. 1994 Aug;24(2):317-22. PMID: 7526067.
