Belladonnine is a member of class of tropane alkaloids. Belladonnine can be found in plants of family Solanaceae. Commercially available preparations called "belladonnine" are sometimes a mixture of this chemical with atropine. β-Belladonnine selectively blocks heart M-receptors (ED50: 13 μg/kg): a blockage of smooth muscles and secretory organs M-cholinoreceptors requires a 10 to 20 times higher concentration. β-Belladonnine also blocks skeletal muscles N-cholinoreceptors (ED50: 50-60 mg/kg).
MedKoo Cat#: 413845
Name: Belladonnine
CAS#: 510-25-8
Chemical Formula: C34H42N2O4
Exact Mass: 542.3145
Molecular Weight: 542.72
Elemental Analysis: C, 75.25; H, 7.80; N, 5.16; O, 11.79
The following data is based on the product molecular weight 542.72 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
