ICR-372 dihydrochloride | CAS# 36167-69-8 | Biochemical

MedKoo Cat#: 576556 | Name: ICR-372 dihydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ICR-372 dihydrochloride is a mutagen.

Chemical Structure

ICR-372 dihydrochloride

CAS#36167-69-8

Theoretical Analysis

MedKoo Cat#: 576556

Name: ICR-372 dihydrochloride

CAS#: 36167-69-8

Chemical Formula: C18H22Cl4N4O

Exact Mass: 450.0548

Molecular Weight: 452.20

Elemental Analysis: C, 47.81; H, 4.90; Cl, 31.36; N, 12.39; O, 3.54

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

ICR 372 dihydrochloride; ICR372 dihydrochloride; ICR-372 dihydrochloride

IUPAC/Chemical Name

1,3-Propanediamine, N-(2-chloroethyl)-N'-(7-chloro-2-methoxybenzo(b)-1,5-naphthyridin-10-yl)-, dihydrochloride

InChi Key

LWGQNPCCIGPMNB-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H20Cl2N4O.2ClH/c1-25-16-6-5-14-18(24-16)17(22-9-2-8-21-10-7-19)13-4-3-12(20)11-15(13)23-14;;/h3-6,11,21H,2,7-10H2,1H3,(H,22,23);2*1H

SMILES Code

Cl.Cl.COc1ccc2nc3cc(Cl)ccc3c(NCCCNCCCl)c2n1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 452.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Hoffmann GR, Morgan RW, Harvey RC. Effects of chemical and physical mutagens on the frequency of a large genetic duplication in Salmonella typhimurium. I. Induction of duplications. Mutat Res. 1978 Oct;52(1):73-80. doi: 10.1016/0027-5107(78)90096-9. PMID: 366399. 2. Hoffmann GR, Freemer CS, Parente LA. Induction of genetic duplications and frameshift mutations in Salmonella typhimurium by acridines and acridine mustards: dependence on covalent binding of the mutagen to DNA. Mol Gen Genet. 1989 Sep;218(3):377-83. doi: 10.1007/BF00332398. PMID: 2479818.