MedKoo Cat#: 464551 | Name: Iocarmic acid

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Iocarmic acid (trade name Dimer-X) is a pharmaceutical drug used as an iodinated contrast medium for X-ray imaging in the 1970s and 80s. Uses included imaging of the uterus and Fallopian tubes. It was applied in form of its salt, meglumine iocarmate. It is not known to be marketed anywhere in the world in 2021.

Chemical Structure

Iocarmic acid
Iocarmic acid
CAS#10397-75-8

Theoretical Analysis

MedKoo Cat#: 464551

Name: Iocarmic acid

CAS#: 10397-75-8

Chemical Formula: C24H20I6N4O8

Exact Mass: 1253.5549

Molecular Weight: 1253.87

Elemental Analysis: C, 22.99; H, 1.61; I, 60.73; N, 4.47; O, 10.21

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Iocarmic acid; Dimer-X; DimerX; Dimer X;
IUPAC/Chemical Name
5,5'-(adipoylbis(azanediyl))bis(2,4,6-triiodo-3-(methylcarbamoyl)benzoic acid)
InChi Key
SMQYOVYWPWASGU-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H20I6N4O8/c1-31-21(37)9-13(25)11(23(39)40)17(29)19(15(9)27)33-7(35)5-3-4-6-8(36)34-20-16(28)10(22(38)32-2)14(26)12(18(20)30)24(41)42/h3-6H2,1-2H3,(H,31,37)(H,32,38)(H,33,35)(H,34,36)(H,39,40)(H,41,42)
SMILES Code
CNC(c1c(I)c(C(O)=O)c(I)c(NC(CCCCC(Nc2c(I)c(C(NC)=O)c(I)c(C(O)=O)c2I)=O)=O)c1I)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,253.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Cheung HS, Johansen JG, Haughton VM, Nichols TR. In vitro testing for the risk of arachnoiditis from myelographic contrast media. Invest Radiol. 1985 Aug;20(5):472-5. doi: 10.1097/00004424-198508000-00006. PMID: 4044192. 2: Webb JA. The effect of intravenous contrast medium on glomerular filtration rate. Br J Radiol. 1984 May;57(677):387-93. doi: 10.1259/0007-1285-57-677-387. PMID: 6722433. 3: Webb JA. The role of the distal nephron mechanisms in the concentration of contrast medium in the urine. Br J Radiol. 1984 May;57(677):381-6. doi: 10.1259/0007-1285-57-677-381. PMID: 6722432. 4: Haughton VM, Ho KC. Arachnoiditis from myelography with iopamidol, metrizamide, and iocarmate compared in the animal model. Invest Radiol. 1980 Nov-Dec;15(6 Suppl):S267. doi: 10.1097/00004424-198011001-00057. PMID: 7203934.