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MedKoo Cat#: 464542 | Name: LM229

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LM229 is novel Probe for Imaging Tau Pathology in Transgenic Mouse and Rat Models.

Chemical Structure

LM229
LM229
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 464542

Name: LM229

CAS#: unknown

Chemical Formula: C17H14FN3OS

Exact Mass: 327.0842

Molecular Weight: 327.38

Elemental Analysis: C, 62.37; H, 4.31; F, 5.80; N, 12.84; O, 4.89; S, 9.79

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
LM229; LM 229; LM-229; LM3-229; LM3229; LM3 229;
IUPAC/Chemical Name
5-fluoro-2-((1E,3E)-4-(6-(methylamino)pyridin-3-yl)buta-1,3-dien-1-yl)benzo[d]thiazol-6-ol
InChi Key
WUXOHZAHRYNBDQ-ZUVMSYQZSA-N
InChi Code
InChI=1S/C17H14FN3OS/c1-19-16-7-6-11(10-20-16)4-2-3-5-17-21-13-8-12(18)14(22)9-15(13)23-17/h2-10,22H,1H3,(H,19,20)/b4-2+,5-3+
SMILES Code
OC1=C(F)C=C2N=C(/C=C/C=C/C3=CC=C(NC)N=C3)SC2=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 327.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: McMurray L, Macdonald JA, Ramakrishnan NK, Zhao Y, Williamson DW, Tietz O, Zhou X, Kealey S, Fagan SG, Smolek T, Cubinkova V, Žilka N, Spillantini MG, Tolkovsky AM, Goedert M, Aigbirhio FI. Synthesis and Assessment of Novel Probes for Imaging Tau Pathology in Transgenic Mouse and Rat Models. ACS Chem Neurosci. 2021 Mar 10. doi: 10.1021/acschemneuro.0c00790. Epub ahead of print. PMID: 33689290.