TPP-d4 is intended for use as an internal standard for the quantification of (4-carboxybutyl)triphenylphosphonium by GC- or LC-MS. (4-Carboxybutyl)triphenylphosphonium is a Wittig reagent. It has been used in the synthesis of prostaglandin F2α (PGF2α; Item No. 16010) and the monounsaturated fatty acid 7-methyl-6-octadecenoic acid. (4-Carboxybutyl)triphenylphosphonium has also been used to enhance mitochondrial localization of albumin nanoparticles loaded with the anticancer agent docetaxel (Item No. 11637).
MedKoo Cat#: 464507
Name: TPP-d4
CAS#: 42932-63-8
Chemical Formula: C23H20D4BrO2P
Exact Mass: 446.0948
Molecular Weight: 447.35
Elemental Analysis: C, 61.75; H, 6.31; Br, 17.86; O, 7.15; P, 6.92
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMF | 5.0 | 11.00 | |
| DMSO | 5.0 | 11.00 | |
| Ethanol | 1.0 | 2.20 | |
| PBS (pH 7.2) | 10.0 | 22.00 |
The following data is based on the product molecular weight 447.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
