ICI-153066 | CAS# 76674-22-1 | Biochemical

MedKoo Cat#: 576513 | Name: ICI-153066

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ICI-153066 is a triazole antifungal antibiotic.

Chemical Structure

ICI-153066

CAS#76674-22-1

Theoretical Analysis

MedKoo Cat#: 576513

Name: ICI-153066

CAS#: 76674-22-1

Chemical Formula: C16H12Cl2FN3O

Exact Mass: 351.0341

Molecular Weight: 352.19

Elemental Analysis: C, 54.57; H, 3.43; Cl, 20.13; F, 5.39; N, 11.93; O, 4.54

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

ICI-153066; ICI 153066; ICI153066

IUPAC/Chemical Name

1H-1,2,4-Triazole-1-ethanol, alpha-(2,4-dichlorophenyl)-alpha-(4-fluorophenyl)-

InChi Key

RBNYRMJSBJAEIA-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H12Cl2FN3O/c17-12-3-6-14(15(18)7-12)16(23,8-22-10-20-9-21-22)11-1-4-13(19)5-2-11/h1-7,9-10,23H,8H2

SMILES Code

OC(Cn1cncn1)(c2ccc(F)cc2)c3ccc(Cl)cc3Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 352.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Hitchcock CA, Barrett-Bee KJ, Russell NJ. The lipid composition and permeability to the triazole antifungal antibiotic ICI 153066 of serum-grown mycelial cultures of Candida albicans. J Gen Microbiol. 1989 Jul;135(7):1949-55. doi: 10.1099/00221287-135-7-1949. PMID: 2693607. 2. Hitchcock CA, Dickinson K, Brown SB, Evans EG, Adams DJ. Interaction of azole antifungal antibiotics with cytochrome P-450-dependent 14 alpha-sterol demethylase purified from Candida albicans. Biochem J. 1990 Mar 1;266(2):475-80. doi: 10.1042/bj2660475. PMID: 2180400; PMCID: PMC1131156.