ICI-222155 | CAS# 132414-04-1 | Biochemical

MedKoo Cat#: 576501 | Name: ICI-222155

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ICI-222155 is an aldose reductase inhibitor.

Chemical Structure

ICI-222155

CAS#132414-04-1

Theoretical Analysis

MedKoo Cat#: 576501

Name: ICI-222155

CAS#: 132414-04-1

Chemical Formula: C9H12N2O4S

Exact Mass: 244.0518

Molecular Weight: 244.26

Elemental Analysis: C, 44.25; H, 4.95; N, 11.47; O, 26.20; S, 13.13

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

ICI 222155; ICI222155; ICI-222155

IUPAC/Chemical Name

4-Amino-2,6-dimethylphenylsulfonyl nitromethane

InChi Key

FIMPGOJEDMNMHL-UHFFFAOYSA-N

InChi Code

InChI=1S/C9H12N2O4S/c1-6-3-8(10)4-7(2)9(6)16(14,15)5-11(12)13/h3-4H,5,10H2,1-2H3

SMILES Code

Cc1cc(N)cc(C)c1S(=O)(=O)C[N+](=O)[O-]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 244.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Cunha JM, Jolivalt CG, Ramos KM, Gregory JA, Calcutt NA, Mizisin AP. Elevated lipid peroxidation and DNA oxidation in nerve from diabetic rats: effects of aldose reductase inhibition, insulin, and neurotrophic factors. Metabolism. 2008 Jul;57(7):873-81. doi: 10.1016/j.metabol.2008.01.021. PMID: 18555826; PMCID: PMC2518323. 2. Calcutt NA, Li L, Yaksh TL, Malmberg AB. Different effects of two aldose reductase inhibitors on nociception and prostaglandin E. Eur J Pharmacol. 1995 Oct 16;285(2):189-97. doi: 10.1016/0014-2999(95)00402-7. PMID: 8566138.