MedKoo Cat#: 576491 | Name: ICI-164384

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ICI-164384 is an estrogen antagonist.

Chemical Structure

ICI-164384
ICI-164384
CAS#98007-99-9

Theoretical Analysis

MedKoo Cat#: 576491

Name: ICI-164384

CAS#: 98007-99-9

Chemical Formula: C34H55NO3

Exact Mass: 525.4182

Molecular Weight: 525.82

Elemental Analysis: C, 77.66; H, 10.54; N, 2.66; O, 9.13

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
ICI 164384; ICI164384; ICI-164384; ICIM164384; ICI-M164384; ICI M164384
IUPAC/Chemical Name
Estra-1,3,5(10)-triene-7-undecanamide, N-butyl-3,17-dihydroxy-N-methyl-, (7alpha,17beta)-
InChi Key
BVVFOLSZMQVDKV-KXQIQQEYSA-N
InChi Code
InChI=1S/C34H55NO3/c1-4-5-22-35(3)32(38)15-13-11-9-7-6-8-10-12-14-25-23-26-24-27(36)16-17-28(26)29-20-21-34(2)30(33(25)29)18-19-31(34)37/h16-17,24-25,29-31,33,36-37H,4-15,18-23H2,1-3H3/t25-,29-,30+,31+,33-,34+/m1/s1
SMILES Code
CCCCN(C)C(=O)CCCCCCCCCC[C@@H]1Cc2cc(O)ccc2[C@H]3CC[C@]4(C)[C@@H](O)CC[C@H]4[C@H]13
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 525.82 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Nicholson RI, Gee JM, Manning DL, Wakeling AE, Montano MM, Katzenellenbogen BS. Responses to pure antiestrogens (ICI 164384, ICI 182780) in estrogen-sensitive and -resistant experimental and clinical breast cancer. Ann N Y Acad Sci. 1995 Jun 12;761:148-63. doi: 10.1111/j.1749-6632.1995.tb31376.x. PMID: 7625718. 2. Coradini D, Biffi A, Pirronello E, Di Fronzo G. The effect of ICI 164384 and beta-interferon on the growth and steroid receptor profile of breast cancer cell lines. Anticancer Res. 1995 Nov-Dec;15(6B):2557-61. PMID: 8669823.