IUPAC/Chemical Name
5-methoxy-2,2-dimethyl-6-(3-methylbut-2-en-1-yl)-2H,8H-pyrano[2,3-f]chromen-8-one
InChi Key
NOGMHSRRWYDWTM-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H22O4/c1-12(2)6-7-13-17(22-5)15-10-11-20(3,4)24-19(15)14-8-9-16(21)23-18(13)14/h6,8-11H,7H2,1-5H3
SMILES Code
COc1c2c(OC(C)(C=C2)C)c3c(OC(C=C3)=O)c1C/C=C(C)\C
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
326.39
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Schlott B, Wöhnert J, Icke C, Hartmann M, Ramachandran R, Gührs KH, Glusa E, Flemming J, Görlach M, Grosse F, Ohlenschläger O. Interaction of Kazal-type inhibitor domains with serine proteinases: biochemical and structural studies. J Mol Biol. 2002 Apr 26;318(2):533-46. doi: 10.1016/S0022-2836(02)00014-1. PMID: 12051857.
2: Jadhav A, Dash R, Hirwani R, Abdin M. Sequence and structure insights of kazal type thrombin inhibitor protein: Studied with phylogeny, homology modeling and dynamic MM/GBSA studies. Int J Biol Macromol. 2018 Mar;108:1045-1052. doi: 10.1016/j.ijbiomac.2017.11.020. Epub 2017 Nov 10. PMID: 29129633.
3: Icke C, Schlott B, Ohlenschläger O, Hartmann M, Gührs KH, Glusa E. Fusion proteins with anticoagulant and fibrinolytic properties: functional studies and structural considerations. Mol Pharmacol. 2002 Aug;62(2):203-9. doi: 10.1124/mol.62.2.203. PMID: 12130670.
4: Carella M, Ramachandran R, Schlott B, Leppert J, Glusa E, Ohlenschläger O. (1)H, (13)C and (15)N sequence-specific resonance assignments of the two-domain thrombin inhibitor dipetalin. J Biomol NMR. 2004 Nov;30(3):383-4. doi: 10.1007/s10858-004-3496-4. PMID: 15754063.
