MedKoo Cat#: 464426 | Name: Sepharose

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sepharose is a tradename for a crosslinked, beaded-form of agarose, a polysaccharide polymer material extracted from seaweed. Its brand name is a portmanteau derived from Separation-Pharmacia-Agarose. A common application for the material is in chromatographic separations of biomolecules.

Chemical Structure

Sepharose
CAS#9012-36-6

Theoretical Analysis

MedKoo Cat#: 464426

Name: Sepharose

CAS#: 9012-36-6

Chemical Formula: C24H38O19

Exact Mass: 630.2007

Molecular Weight: 630.55

Elemental Analysis: C, 45.72; H, 6.07; O, 48.21

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Sepharose; Agarose; Agarose gel beads;
IUPAC/Chemical Name
(2S,3R,4S,5R,6R)-2-(((1S,3S,4S,5S,8R)-3-(((2S,3R,4S,5S,6R)-2-(((1S,3R,4S,5S,8R)-3,4-dihydroxy-2,6-dioxabicyclo[3.2.1]octan-8-yl)oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-4-hydroxy-2,6-dioxabicyclo[3.2.1]octan-8-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
InChi Key
MJQHZNBUODTQTK-WKGBVCLCSA-N
InChi Code
InChI=1S/C24H38O19/c25-1-5-9(27)11(29)12(30)22(38-5)41-17-8-4-36-20(17)15(33)24(40-8)43-18-10(28)6(2-26)39-23(14(18)32)42-16-7-3-35-19(16)13(31)21(34)37-7/h5-34H,1-4H2/t5-,6-,7+,8+,9+,10+,11+,12-,13+,14-,15+,16-,17-,18+,19+,20+,21-,22+,23+,24+/m1/s1
SMILES Code
OC[C@H]1O[C@H]([C@@H]([C@H]([C@H]1O)O)O)O[C@@H]2[C@@H]3CO[C@H]2[C@@H]([C@@H](O3)O[C@H]4[C@H]([C@H](O[C@H]([C@@H]4O)O[C@@H]5[C@@H]6CO[C@H]5[C@@H]([C@@H](O6)O)O)CO)O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 630.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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Peptidoglycan-Binding Anchor Is a Pseudomonas aeruginosa OmpA Family Lipoprotein With Importance for Outer Membrane Vesicles, Biofilms, and the Periplasmic Shape. Front Microbiol. 2021 Feb 25;12:639582. doi: 10.3389/fmicb.2021.639582. PMID: 33717034; PMCID: PMC7947798. 5: Wan Y, Fan H, Gao L, Li R, Xie M, Wu C, Chen L, Fu G. The Change Mechanism of Structural Characterization and Thermodynamic Properties of Tannase from Aspergillus niger NL112 Under High Temperature. Appl Biochem Biotechnol. 2021 Mar 9. doi: 10.1007/s12010-021-03488-x. Epub ahead of print. PMID: 33686629. 6: Zhao M, Bai J, Bu X, Yin Y, Wang L, Yang Y, Xu Y. Characterization of selenized polysaccharides from Ribes nigrum L. and its inhibitory effects on α-amylase and α-glucosidase. Carbohydr Polym. 2021 May 1;259:117729. doi: 10.1016/j.carbpol.2021.117729. Epub 2021 Feb 3. PMID: 33673993. 7: Wu SC, Paul A, Ho A, Patel KR, Allen JWL, Verkerke H, Arthur CM, Stowell SR. Generation and Use of Recombinant Galectins. Curr Protoc. 2021 Mar;1(3):e63. doi: 10.1002/cpz1.63. PMID: 33656274. 8: Tan S, Saito K, Hearn MTW. Isothermal modelling of protein adsorption to thermo-responsive polymer grafted Sepharose Fast Flow sorbents. J Sep Sci. 2021 Mar 1. doi: 10.1002/jssc.202001188. Epub ahead of print. PMID: 33650274. 9: Hirschberg D, Ekman B, Wahlberg J, Landberg E. Altered immunoglobulin G glycosylation in patients with isolated hyperprolactinaemia. PLoS One. 2021 Feb 26;16(2):e0247805. doi: 10.1371/journal.pone.0247805. PMID: 33635916; PMCID: PMC7909626. 10: Li H, Li Y, Hu J, Liu S, Luo X, Tang M, Bode AM, Dong Z, Liu X, Liao W, Cao Y. (-)-Epigallocatechin-3-gallate inhibits EBV lytic replication via targeting LMP1-mediated MAPK signal axes. Oncol Res. 2021 Feb 17. doi: 10.3727/096504021X16135618512563. Epub ahead of print. PMID: 33629943. 11: Tan YH, Alias Z. Expression of cytosolic and thiolated proteome of Musca domestica larvae under oxidative challenge. Trop Biomed. 2020 Sep 1;37(3):744-755. doi: 10.47665/tb.37.3.744. PMID: 33612787. 12: Qiu Y, Jiang H, Fu L, Ci F, Mao X. Porphyran and oligo-porphyran originating from red algae Porphyra: Preparation, biological activities, and potential applications. Food Chem. 2021 Jul 1;349:129209. doi: 10.1016/j.foodchem.2021.129209. Epub 2021 Feb 2. PMID: 33588184. 13: Tsikas D. Extra-platelet low-molecular-mass thiols mediate the inhibitory action of S-nitrosoalbumin on human platelet aggregation via S-transnitrosylation of the platelet surface. Amino Acids. 2021 Feb 14. doi: 10.1007/s00726-021-02950-8. Epub ahead of print. PMID: 33586042. 14: Cutiño-Avila BV, Sánchez-López MI, Cárdenas-Moreno Y, González-Durruthy M, Ramos-Leal M, Guerra-Rivera G, González-Bacerio J, Guisán JM, Ruso JM, Del Monte-Martínez A. Modeling and experimental validation of covalent immobilization of Trametes maxima laccase on glyoxyl and MANA-Sepharose CL 4B supports, for the use in bioconversion of residual colorants. Biotechnol Appl Biochem. 2021 Feb 12. doi: 10.1002/bab.2125. Epub ahead of print. PMID: 33580532. 15: Greiner R. Preparation of pure lower-order myo-Inositol phosphates on laboratory scale for physiological and enzymatic studies. Prep Biochem Biotechnol. 2021 Feb 10:1-5. doi: 10.1080/10826068.2021.1881909. Epub ahead of print. PMID: 33565914. 16: Hao D, Zhang R, Ge J, Ye P, Song C, Zhu K, Na X, Huang Y, Zhao L, Zhou W, Su Z, Ma G. Rapid and high-capacity loading of IgG monoclonal antibodies by polymer brush and peptides functionalized microspheres. J Chromatogr A. 2021 Mar 15;1640:461948. doi: 10.1016/j.chroma.2021.461948. Epub 2021 Jan 30. PMID: 33561708. 17: Song Y, Cui Y, Hao L, Zhu J, Yi J, Kang Q, Huang J, Lu J. Wound-healing activity of glycoproteins from white jade snail (Achatina fulica) on experimentally burned mice. Int J Biol Macromol. 2021 Apr 1;175:313-321. doi: 10.1016/j.ijbiomac.2021.01.193. Epub 2021 Feb 1. 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