Synonym
                                        Etoglucid; ICI32865; ICI-32865; ICI 32865
                                     
                                    
                                        IUPAC/Chemical Name
                                        1,12-di(oxiran-2-yl)-2,5,8,11-tetraoxadodecane
                                     
                                    
                                        InChi Key
                                        UMILHIMHKXVDGH-UHFFFAOYSA-N
                                     
                                    
                                        InChi Code
                                        InChI=1S/C12H22O6/c1(13-3-5-15-7-11-9-17-11)2-14-4-6-16-8-12-10-18-12/h11-12H,1-10H2
                                     
                                    
                                        SMILES Code
                                        C1(CO1)COCCOCCOCCOCC2CO2
                                     
                                    
                                    
                                        Purity
                                        >98% (or refer to the Certificate of Analysis)
                                     
                                    
                                        Shipping Condition
                                        Shipped under ambient temperature as non-hazardous chemical.  This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
                                     
                                    
                                        Storage Condition
                                        Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
                                     
                                    
                                        Solubility
                                        To be determined
                                     
                                    
                                        Shelf Life
                                        >2 years if stored properly
                                     
                                    
                                        Drug Formulation
                                        To be determined
                                     
                                    
                                        Stock Solution Storage
                                        0 - 4 C for short term (days to weeks), or -20 C for long term (months).
                                     
                                    
                                        HS Tariff Code
                                        2934.99.9001
                                     
                                    
                                 
                             
                            
                                                        
                                                                
                                    Preparing Stock Solutions
                                    
                                        The following data is based on the
                                        product
                                        molecular weight
                                        262.30
                                        Batch specific molecular weights may vary
                                        from batch to batch
                                        due to the degree of hydration, which will
                                        affect the solvent
                                        volumes required to prepare stock solutions.
                                    
                                    
                                    
                                        
                                            
                                            
                                                | Concentration / Solvent Volume / Mass | 
                                                1 mg | 
                                                5 mg | 
                                                10 mg | 
                                            
                                            
                                            
                                            
                                                | 1 mM | 
                                                1.15 mL | 
                                                5.76 mL | 
                                                11.51 mL | 
                                            
                                            
                                                | 5 mM | 
                                                0.23 mL | 
                                                1.15 mL | 
                                                2.3 mL | 
                                            
                                            
                                                | 10 mM | 
                                                0.12 mL | 
                                                0.58 mL | 
                                                1.15 mL | 
                                            
                                            
                                                | 50 mM | 
                                                0.02 mL | 
                                                0.12 mL | 
                                                0.23 mL | 
                                            
                                            
                                        
                                     
                                 
                                                             
                            
                            
                                
                                    1: Flamm J, Donner G, Bucher A, Höltl W, Albrecht W, Havelec L. Topische Immuntherapie (KLH) vs. Chemotherapie (Ethoglucid) in der Rezidivprophylaxe oberflächlicher Harnblasenkarzinome. Eine prospektiv randomisierte Studie [Topical immunotherapy (KLH) vs. chemotherapy (Ethoglucid) in prevention of recurrence of superficial bladder cancer. A prospective randomized study]. Urologe A. 1994 Mar;33(2):138-43. German. PMID: 8178408.
2: Thrasher JB, Crawford ED. Complications of intravesical chemotherapy. Urol Clin North Am. 1992 Aug;19(3):529-39. PMID: 1636237.
3: Sonneveld P, Kurth KH, Hagemeyer A, Abels J. Secondary hematologic neoplasm after intravesical chemotherapy for superficial bladder carcinoma. Cancer. 1990 Jan 1;65(1):23-5. doi: 10.1002/1097-0142(19900101)65:1<23::aid- cncr2820650107>3.0.co;2-q. PMID: 2104570.
4: Veenema RJ, Romas NA, Fingerhut B. Chemotherapy for bladder cancer. Urology. 1974 Feb;3(2):135-9. doi: 10.1016/s0090-4295(74)80001-4. PMID: 4204755.
5: Condon HA. Hypothermia and cancer chemotherapy. Anesth Analg. 1969 Jan- Feb;48(1):92-8. PMID: 5812564.
6: Soloway MS. Intravesical and systemic chemotherapy of murine bladder cancer. Cancer Res. 1977 Aug;37(8 Pt 2):2918-29. PMID: 406041.
7: Schmidt CG. Alkylierende cytostatica [Alkylating cytostatic agents]. Internist (Berl). 1971;12:Suppl 1:119-27. German. PMID: 5002874.
8: Torti FM, Lum BL. The biology and treatment of superficial bladder cancer. J Clin Oncol. 1984 May;2(5):505-31. doi: 10.1200/JCO.1984.2.5.505. PMID: 6427417.
9: Highley MS, van Oosterom AT, Maes RA, De Bruijn EA. Intravesical drug delivery. Pharmacokinetic and clinical considerations. Clin Pharmacokinet. 1999 Jul;37(1):59-73. doi: 10.2165/00003088-199937010-00004. PMID: 10451783.
10: Flamm J, Kühnel W, Dona S. Kurzzeit- versus Langzeitchemorezidivprophylaxe mit Epodyl nach TUR beim oberflächlichen Harnblasenkarzinom [Short-term versus long-term chemoprevention of recurrence with Epodyl following transurethral resection of superficial urinary bladder cancer]. Urologe A. 1989 Mar;28(2):99-102. German. PMID: 2655259.