MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 464418 | Name: Piperitone
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Piperitone is a monoterpenoid that has been found in Mentha and has diverse biological activities. Piperitone is active against E. coli, P. aeruginosa, S. typhimurium, S. aureus, R. leguminosarum, and B. subtilis in agar diffusion assays. Piperitone enhances the antibacterial activity of nitrofurantoin against several nitrofurantoin-resistant species of Enterobacteriaceae, including C. freundii, E. coli, and S. marcescens, by 3- to 20-fold. It exhibits feeding deterrent and repellent activities against ants (Crematogaster) with 80% deterrence index (D80) and 80% repellent index (R80) values of 0.13 µg/µl and 8.9 µg/cm2, respectively. Piperitone is insecticidal against C. maculatus eggs, larvae, and adults.

Chemical Structure

Piperitone
Piperitone
CAS#89-81-6

Theoretical Analysis

MedKoo Cat#: 464418

Name: Piperitone

CAS#: 89-81-6

Chemical Formula: C10H16O

Exact Mass: 152.1201

Molecular Weight: 152.24

Elemental Analysis: C, 78.90; H, 10.59; O, 10.51

Price and Availability

Size Price Availability Quantity
5mg USD 310.00 2 Weeks
10mg USD 550.00 2 Weeks
50mg USD 740.00 2 Weeks
100mg USD 1,040.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Piperitone; 3-Carvomenthenone; 3 Carvomenthenone; NSC 251528; NSC251528; NSC-251528;
IUPAC/Chemical Name
6-isopropyl-3-methylcyclohex-2-en-1-one
InChi Key
YSTPAHQEHQSRJD-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H16O/c1-7(2)9-5-4-8(3)6-10(9)11/h6-7,9H,4-5H2,1-3H3
SMILES Code
O=C1C=C(C)CCC1C(C)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Product Data
Instruction
View handling instruction
Biological target:
Piperitone is a powerful repellent and antiappetent agent.
In vitro activity:
TBD
In vivo activity:
TBD
Solvent mg/mL mM comments
Solubility
Ethanol 30.0 197.06
Ethanol:PBS (pH 7.2) (1:6) 0.1 0.92
DMSO 100.0 656.87
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 152.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Bai X, Liu L, Zhang J, Chen L, Wu T, Aisa HA, Maiwulanjiang M. Spectrum- effect relationship between GC-QTOF-MS fingerprint and antioxidant, anti- inflammatory activities of Schizonepeta tenuifolia essential oil. Biomed Chromatogr. 2021 Feb 27:e5106. doi: 10.1002/bmc.5106. Epub ahead of print. PMID: 33638568. 2: Hou Z, Liu J, Cai M, Liu Y, Mu L, Gao Y, Wanapat M, Huang B. Enriching the nutritive value of marigold (Tagetes erecta L) crop residues as a ruminant feed by lactic acid bacteria during ensilage. BMC Vet Res. 2021 Feb 12;17(1):74. doi: 10.1186/s12917-021-02762-8. PMID: 33579276; PMCID: PMC7881656. 3: Fei X, Qi Y, Lei Y, Wang S, Hu H, Wei A. Transcriptome and Metabolome Dynamics Explain Aroma Differences between Green and Red Prickly Ash Fruit. Foods. 2021 Feb 10;10(2):391. doi: 10.3390/foods10020391. PMID: 33579038; PMCID: PMC7916813. 4: Nishida T, Satoh K, Kamigaito M. Biobased Polymers via Radical Homopolymerization and Copolymerization of a Series of Terpenoid-Derived Conjugated Dienes with exo-Methylene and 6-Membered Ring. Molecules. 2020 Dec 12;25(24):5890. doi: 10.3390/molecules25245890. PMID: 33322773; PMCID: PMC7763260. 5: Debbabi H, El Mokni R, Nardoni S, Chaieb I, Maggi F, Nzekoue FK, Caprioli G, Hammami S. Chemical diversity and biological activities of essential oils from native populations of Clinopodium menthifolium subsp. ascendens (Jord.) Govaerts. Environ Sci Pollut Res Int. 2021 Mar;28(11):13624-13633. doi: 10.1007/s11356-020-11523-3. Epub 2020 Nov 14. PMID: 33190203. 6: Verdeguer M, Roselló J, Castell V, Llorens JA, Santamarina MP. Cherry tomato and persimmon kaki conservation with a natural and biodegradable film. Curr Res Food Sci. 2019 Dec 12;2:33-40. doi: 10.1016/j.crfs.2019.11.005. Erratum in: Curr Res Food Sci. 2020 Apr 16;3:339-340. PMID: 32914109; PMCID: PMC7473364. 7: Dehyab AS, Bakar MFA, AlOmar MK, Sabran SF. A review of medicinal plant of Middle East and North Africa (MENA) region as source in tuberculosis drug discovery. Saudi J Biol Sci. 2020 Sep;27(9):2457-2478. doi: 10.1016/j.sjbs.2020.07.007. Epub 2020 Jul 10. PMID: 32884430; PMCID: PMC7451596. 8: Chaves RDSB, Martins RL, Rodrigues ABL, Rabelo ÉM, Farias ALF, Brandão LB, Santos LL, Galardo AKR, de Almeida SSMDS. Evaluation of larvicidal potential against larvae of Aedes aegypti (Linnaeus, 1762) and of the antimicrobial activity of essential oil obtained from the leaves of Origanum majorana L. PLoS One. 2020 Jul 17;15(7):e0235740. doi: 10.1371/journal.pone.0235740. PMID: 32678859; PMCID: PMC7367459. 9: Byers JA, Maoz Y, Fefer D, Levi-Zada A. Semiochemicals Affecting Attraction of Ambrosia Beetle Euwallacea fornicatus (Coleoptera: Curculionidae: Scolytinae) to Quercivorol: Developing Push-Pull Control. J Econ Entomol. 2020 Oct 16;113(5):2120-2127. doi: 10.1093/jee/toaa127. PMID: 32596735. 10: Ahadi N, Torabbeigi M, Aghaiee Meibodei Z, Safatian F. Volatile Components of Haplophyllum canaliculatum Boiss. by Different Extraction Procedures. J Anal Methods Chem. 2020 May 30;2020:4202871. doi: 10.1155/2020/4202871. PMID: 32566357; PMCID: PMC7277027. 11: Iraji A, Yazdanpanah S, Alizadeh F, Mirzamohammadi S, Ghasemi Y, Pakshir K, Yang Y, Zomorodian K. Screening the antifungal activities of monoterpenes and their isomers against Candida species. J Appl Microbiol. 2020 Dec;129(6):1541-1551. doi: 10.1111/jam.14740. Epub 2020 Jul 9. PMID: 32506599. 12: Debbabi H, Mokni RE, Chaieb I, Nardoni S, Maggi F, Caprioli G, Hammami S. Chemical Composition, Antifungal and Insecticidal Activities of the Essential Oils from Tunisian Clinopodium Nepeta Subsp. nepeta and Clinopodium Nepeta Subsp. Glandulosum. Molecules. 2020 May 2;25(9):2137. doi: 10.3390/molecules25092137. PMID: 32370305; PMCID: PMC7249092. 13: Chiou TY, Nomura S, Konishi M, Liao CS, Shimotori Y, Murata M, Ohtsu N, Kohari Y, Lee WJ, Tsai TY, Nagata Y, Saitoh T. Conversion and Hydrothermal Decomposition of Major Components of Mint Essential Oil by Small-Scale Subcritical Water Treatment. Molecules. 2020 Apr 22;25(8):1953. doi: 10.3390/molecules25081953. PMID: 32331471; PMCID: PMC7221780. 14: Singh N, Singh HP, Batish DR, Kohli RK, Yadav SS. Chemical characterization, phytotoxic, and cytotoxic activities of essential oil of Mentha longifolia. Environ Sci Pollut Res Int. 2020 Apr;27(12):13512-13523. doi: 10.1007/s11356-020-07823-3. Epub 2020 Feb 5. PMID: 32303127. 15: Aminkhani A, Sharifi S, Ekhtiyari S. Achillea filipendulina Lam.: Chemical Constituents and Antimicrobial Activities of Essential Oil of Stem, Leaf, and Flower. Chem Biodivers. 2020 May;17(5):e2000133. doi: 10.1002/cbdv.202000133. Epub 2020 Apr 29. PMID: 32239617. 16: Thibaud F, Courregelongue M, Darriet P. Contribution of Volatile Odorous Terpenoid Compounds to Aged Cognac Spirits Aroma in a Context of Multicomponent Odor Mixtures. J Agric Food Chem. 2020 Nov 25;68(47):13310-13318. doi: 10.1021/acs.jafc.9b06656. Epub 2020 Feb 21. PMID: 32052967. 17: Yener I, Yilmaz MA, Olmez OT, Akdeniz M, Tekin F, Hasimi N, Alkan MH, Ozturk M, Ertas A. A Detailed Biological and Chemical Investigation of Sixteen Achillea Species' Essential Oils via Chemometric Approach. Chem Biodivers. 2020 Mar;17(3):e1900484. doi: 10.1002/cbdv.201900484. Epub 2020 Feb 20. PMID: 31999042. 18: Masila VM, Ndakala AJ, Byamukama R, Midiwo JO, Kamau RW, Wang M, Kumarihamy M, Zhao J, Heydreich M, Muhammad I. Synthesis, structural assignments and antiinfective activities of 3-O-benzyl-carvotacetone and 3-hydroxy-2-isopropyl-5-methyl-p-benzoquinone. Nat Prod Res. 2020 Jan 30:1-9. doi: 10.1080/14786419.2020.1716346. Epub ahead of print. PMID: 31997645. 19: Yagi S, Mohammed ABA, Tzanova T, Schohn H, Abdelgadir H, Stefanucci A, Mollica A, Zengin G. Chemical profile, antiproliferative, antioxidant, and enzyme inhibition activities and docking studies of Cymbopogon schoenanthus (L.) Spreng. and Cymbopogon nervatus (Hochst.) Chiov. from Sudan. J Food Biochem. 2020 Feb;44(2):e13107. doi: 10.1111/jfbc.13107. Epub 2019 Dec 6. PMID: 31808956. 20: El-Mustapha L, Abderrafea E, Ayoub K, Abdelaziz A, El Hassan EM. Toxicity of essential oils obtained from Juniperus thurifera var. africana and Mentha suaveolens subsp. timija chemotypes against pre-adult stages of Hyalomma aegyptium tick (Acari: Ixodidae). Nat Prod Res. 2019 Oct 17:1-6. doi: 10.1080/14786419.2019.1677658. Epub ahead of print. PMID: 31621402.