HWL-12 | CAS# 160603-60-1 | Biochemical

MedKoo Cat#: 576412 | Name: HWL-12

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HWL-12 is a biochemical with a potent tumor multi-drug resistance (MDR) reversal action.

Chemical Structure

HWL-12

CAS#160603-60-1

Theoretical Analysis

MedKoo Cat#: 576412

Name: HWL-12

CAS#: 160603-60-1

Chemical Formula: C31H33N3O4

Exact Mass: 511.2471

Molecular Weight: 511.62

Elemental Analysis: C, 72.78; H, 6.50; N, 8.21; O, 12.51

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

HWL-12; HWL 12; HWL12

IUPAC/Chemical Name

Methanone, (4-hydroxy-3,5-bis(4-morpholinylmethyl)phenyl)(2-phenyl-1H-indol-3-yl)-

InChi Key

MVEOVXOGZPWVHN-UHFFFAOYSA-N

InChi Code

InChI=1S/C31H33N3O4/c35-30-24(20-33-10-14-37-15-11-33)18-23(19-25(30)21-34-12-16-38-17-13-34)31(36)28-26-8-4-5-9-27(26)32-29(28)22-6-2-1-3-7-22/h1-9,18-19,32,35H,10-17,20-21H2

SMILES Code

Oc1c(CN2CCOCC2)cc(cc1CN3CCOCC3)C(=O)c4c([nH]c5ccccc45)c6ccccc6

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 511.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Fu LW, Pan QC, Huang WL, Yang XP. Reversal of tumor multidrug resistance by 2-phenyl-3-(3',5'-dimorpholinomethyl-4'-hydroxy)-benzoyl-indole (HWL-12). Zhongguo Yao Li Xue Bao. 1998 Jan;19(1):77-80. PMID: 10375766.