HR-375 HCl | CAS# 82117-52-0 | Biochemical

MedKoo Cat#: 576375 | Name: HR-375 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HR-375 HCl is a a potential antipsychotic drug that interacts with dopamine D2 receptors and sigma-receptors in the brain.

Chemical Structure

HR-375 HCl

CAS#82117-52-0

Theoretical Analysis

MedKoo Cat#: 576375

Name: HR-375 HCl

CAS#: 82117-52-0

Chemical Formula: C23H25ClFN3O

Exact Mass: 413.1670

Molecular Weight: 413.92

Elemental Analysis: C, 66.74; H, 6.09; Cl, 8.56; F, 4.59; N, 10.15; O, 3.87

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

HR375 HCl; HR-375 HCl; HR 375 HCl; HR-375 hydrochloride

IUPAC/Chemical Name

1-Butanone, 1-(4-fluorophenyl)-4-(4-(3-isoquinolinyl)-1-piperazinyl)-, monohydrochloride

InChi Key

JZTJTZLBUIZNCX-UHFFFAOYSA-N

InChi Code

InChI=1S/C23H24FN3O.ClH/c24-21-9-7-18(8-10-21)22(28)6-3-11-26-12-14-27(15-13-26)23-16-19-4-1-2-5-20(19)17-25-23;/h1-2,4-5,7-10,16-17H,3,6,11-15H2;1H

SMILES Code

Cl.Fc1ccc(cc1)C(=O)CCCN2CCN(CC2)c3cc4ccccc4cn3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 413.92 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Su TP. HR 375: a potential antipsychotic drug that interacts with dopamine D2 receptors and sigma-receptors in the brain. Neurosci Lett. 1986 Nov 11;71(2):224-8. doi: 10.1016/0304-3940(86)90563-x. PMID: 2878399.