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MedKoo Cat#: 413667 | Name: Diayangambin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Diayangambin is an immunosuppressive and anti-inflammatory agent

Chemical Structure

Diayangambin
CAS#21453-68-9

Theoretical Analysis

MedKoo Cat#: 413667

Name: Diayangambin

CAS#: 21453-68-9

Chemical Formula: C24H30O8

Exact Mass: 446.1941

Molecular Weight: 446.49

Elemental Analysis: C, 64.56; H, 6.77; O, 28.67

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
(+)-Diayangambin; (+)-Syringaresinol dimethyl ether; Diayangambin; Diayangambin, (+)-; Lirioresinol C dimethyl ether; Lirioresinol C, O,O-dimethyl-; O,O-Dimethyllirioresinol C; Syringaresinol dimethyl ether;
IUPAC/Chemical Name
1H,3H-Furo(3,4-c)furan, tetrahydro-1,4-bis(3,4,5-trimethoxyphenyl)-,(1R,3aR,4R,6aR)-
InChi Key
HRLFUIXSXUASEX-QDGJQWLKSA-N
InChi Code
InChI=1S/C24H30O8/c1-25-17-7-13(8-18(26-2)23(17)29-5)21-15-11-32-22(16(15)12-31-21)14-9-19(27-3)24(30-6)20(10-14)28-4/h7-10,15-16,21-22H,11-12H2,1-6H3/t15-,16-,21-,22-/m0/s1
SMILES Code
COC1=C(OC)C(OC)=CC([C@@H]2OC[C@]3([H])[C@H](C4=CC(OC)=C(OC)C(OC)=C4)OC[C@@]32[H])=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 446.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: De León EJ, Olmedo DA, Solís PN, Gupta MP, Terencio MC. Diayangambin exerts immunosuppressive and anti-inflammatory effects in vitro and in vivo. Planta Med. 2002 Dec;68(12):1128-31. doi: 10.1055/s-2002-36355. PMID: 12494343. 2: El-Mekkawy S, Meselhy MR, Nkobole N, Lall N. Three new α-glucosidase inhibitors from guggul, the oleogum resin of Commiphora wightii. Nat Prod Res. 2013;27(2):146-54. doi: 10.1080/14786419.2012.662651. Epub 2012 Mar 1. PMID: 22376270. 3: Solís PN, Olmedo D, Nakamura N, Calderón ÁI, Hattori M, Gupta MP. A New Larvicidal Lignan from Piper fimbriulatum. Pharm Biol. 2005;43(4):378-381. doi: 10.1080/13880200590951865. PMID: 28925841. 4: Tsai IL, Lee FP, Wu CC, Duh CY, Ishikawa T, Chen JJ, Chen YC, Seki H, Chen IS. New cytotoxic cyclobutanoid amides, a new furanoid lignan and anti-platelet aggregation constituents from Piper arborescens. Planta Med. 2005 Jun;71(6):535-42. doi: 10.1055/s-2005-864155. PMID: 15971125. 5: Butts CA, van Klink JW, Joyce NI, Paturi G, Hedderley DI, Martell S, Harvey D. Composition and safety evaluation of tea from New Zealand kawakawa (Piper excelsum). J Ethnopharmacol. 2019 Mar 25;232:110-118. doi: 10.1016/j.jep.2018.12.029. Epub 2018 Dec 18. PMID: 30572092. 6: Mota Jda S, Leite AC, Kato MJ, Young MC, Bolzani Vda S, Furlan M. Isoswertisin flavones and other constituents from Peperomia obtusifolia. Nat Prod Res. 2011 Jan;25(1):1-7. doi: 10.1080/14786410903244954. PMID: 21240754. 7: Obst K, Lieder B, Reichelt KV, Backes M, Paetz S, Geißler K, Krammer G, Somoza V, Ley JP, Engel KH. Sensory active piperine analogues from Macropiper excelsum and their effects on intestinal nutrient uptake in Caco-2 cells. Phytochemistry. 2017 Mar;135:181-190. doi: 10.1016/j.phytochem.2016.12.016. Epub 2017 Jan 5. PMID: 28065397. 8: Rimando AM, Dayan FE, Mikell JR, Moraes RM. Phytotoxic lignans of Leucophyllum frutescens. Nat Toxins. 1999;7(1):39-43. doi: 10.1002/(sici)1522-7189(199902)7:1<39::aid-nt38>3.0.co;2-2. PMID: 10441036. 9: Yao LJ, Jalil J, Attiq A, Hui CC, Zakaria NA. The medicinal uses, toxicities and anti-inflammatory activity of Polyalthia species (Annonaceae). J Ethnopharmacol. 2019 Jan 30;229:303-325. doi: 10.1016/j.jep.2018.10.001. Epub 2018 Oct 11. PMID: 30316887.