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MedKoo Cat#: 413657 | Name: Dimazole

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dimazole is an antifungal compound.

Chemical Structure

Dimazole
CAS#95-27-2

Theoretical Analysis

MedKoo Cat#: 413657

Name: Dimazole

CAS#: 95-27-2

Chemical Formula: C15H23N3OS

Exact Mass: 293.1562

Molecular Weight: 293.43

Elemental Analysis: C, 61.40; H, 7.90; N, 14.32; O, 5.45; S, 10.93

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Dimazole; Asterol; Diamethazole
IUPAC/Chemical Name
2-Benzothiazolamine, 6-(2-(diethylamino)ethoxy)-N,N-dimethyl-
InChi Key
WGMYEOIMVYADRJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H23N3OS/c1-5-18(6-2)9-10-19-12-7-8-13-14(11-12)20-15(16-13)17(3)4/h7-8,11H,5-6,9-10H2,1-4H3
SMILES Code
CCN(CCOc(cc1)cc2c1nc(N(C)C)s2)CC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 293.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: DIAMTHAZOLE dihydrochloride. J Am Med Assoc. 1957 May 18;164(3):281-2. PMID: 13415982. 2: MORTON K. Convulsions following diamthazole (asterol). AMA J Dis Child. 1960 Jan;99:109. doi: 10.1001/archpedi.1960.02070030111020. PMID: 14424470. 3: GRUNBERG E, TITSWORTH E. Experimental studies on drug resistance of dermatophytes. I. The development of drug resistance of Trichophyton mentagrophytes and Microsporum lanosum to undecylenic acid and 2-dimethyl amino-6-(beta-di-ethylaminoethoxy) benzothiazole dihydrochloride (asterol). J Invest Dermatol. 1955 Aug;25(2):113-5. PMID: 13263683. 4: NEIMANN N, PIERSON M, LASCOMBES G, MANCIAUX M. Intoxication du nourrisson par l'astérol [Asterol poisoning in infants]. Bull Soc Fr Dermatol Syphiligr. 1957 Aug-Oct;39(4):481-2. French. PMID: 13511069. 5: THURSTON DL, HOLOWACH J, O'LEARY JL. Asterol; further search for neurological disturbances. AMA J Dis Child. 1956 Jun;91(6):581-3. doi: 10.1001/archpedi.1956.02060020583010. PMID: 13312897. 6: BULEY HM, KULWIN MH. The effects of sugar deprivation on the anti-fungal properties of asterol; an in vitro study. J Invest Dermatol. 1959 Jul;33(1):19-21. doi: 10.1038/jid.1959.114. PMID: 13673207. 7: VANBREUSEGHEM R, BRUAUX P. Nouvel essai de traitement des teignes du cuir chevelu par l'astérol au Congo belge [New trial of treatment of tinea of the scalp by asterol in the Belgian Congo]. Ann Soc Belg Med Trop (1920). 1957 Dec 31;37(6):933-9. French. PMID: 13534153. 8: RAVITS HG. Treatment of superficial dermatomycoses with asterol dihydrochloride. J Am Med Assoc. 1952 Mar 22;148(12):1005-7. doi: 10.1001/jama.1952.02930120027006. PMID: 14897701. 9: CHRISTEN JP, JACCOTTET M. Intoxications convulsivantes chez l'enfant; meta et astérol [Convulsant poisoning in children; meta & asterol]. Rev Med Suisse Romande. 1957 Sep;77(9):657-73. French. PMID: 13485751. 10: GATTI F, VANBREUSEGHEM R. Traitement des teignes du cuir chevelu par l'astérol chez les indigènes du Congo Belge [Treatment of tinea of scalp in natives of the Belgian Congo by asterol]. Ann Soc Belg Med Trop (1920). 1955 Dec 31;35(6):711-7. French. PMID: 13314325.