MedKoo Cat#: 464353 | Name: Cyclothiocurvularin A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cyclothiocurvularin A is a macrocyclic polyketide that has been found in Penicillium.

Chemical Structure

Cyclothiocurvularin A
Cyclothiocurvularin A
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 464353

Name: Cyclothiocurvularin A

CAS#: unknown

Chemical Formula: C19H22O8S

Exact Mass: 410.1035

Molecular Weight: 410.44

Elemental Analysis: C, 55.60; H, 5.40; O, 31.18; S, 7.81

Price and Availability

Size Price Availability Quantity
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Cyclothiocurvularin A; Cyclothiocurvularin-A;
IUPAC/Chemical Name
(1R,3aR,7S,15aR)-1,12,14-trihydroxy-7-methyl-9,15-dioxo-1,2,3a,4,6,7,9,10,15,15a-decahydro-5H-benzo[d]thieno[3,2-g][1]oxacyclododecine-1-carboxylic acid
InChi Key
CATXBXDAUWOWMZ-RMKKTFRBSA-N
InChi Code
InChI=1S/C19H22O8S/c1-9-3-2-4-13-16(19(26,8-28-13)18(24)25)17(23)15-10(6-14(22)27-9)5-11(20)7-12(15)21/h5,7,9,13,16,20-21,26H,2-4,6,8H2,1H3,(H,24,25)/t9-,13+,16-,19+/m0/s1
SMILES Code
O[C@@]1(CS[C@]([H])(CCC[C@@H](OC(CC2=CC(O)=CC(O)=C2C3=O)=O)C)[C@]13[H])C(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 410.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: de Castro MV, Ióca LP, Williams DE, Costa BZ, Mizuno CM, Santos MF, de Jesus K, Ferreira ÉL, Seleghim MH, Sette LD, Pereira Filho ER, Ferreira AG, Gonçalves NS, Santos RA, Patrick BO, Andersen RJ, Berlinck RG. Condensation of Macrocyclic Polyketides Produced by Penicillium sp. DRF2 with Mercaptopyruvate Represents a New Fungal Detoxification Pathway. J Nat Prod. 2016 Jun 24;79(6):1668-78. doi: 10.1021/acs.jnatprod.6b00295. Epub 2016 May 26. PMID: 27227682.