Rubiginone D2 is a polyketide that has been found in Streptomyces that has antibacterial and anticancer activities. It is active against S. aureus and E. coli, but not B. subtilis, in agar diffusion assays when used at a concentration of 64 µg/disc. Rubiginone D2 inhibits growth of HM02, KATO III, HepG2, and MCF-7 cancer cells (GI50s = 0.1, 0.7, <0.1, and 7.5 µmol/L).
MedKoo Cat#: 464348
Name: Rubiginone D2
CAS#: 274913-71-2
Chemical Formula: C20H16O6
Exact Mass: 352.0947
Molecular Weight: 352.34
Elemental Analysis: C, 68.18; H, 4.58; O, 27.24
The following data is based on the product molecular weight 352.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
