MedKoo Cat#: 464343 | Name: Piliformic Acid
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Piliformic acid is a fungal metabolite that has been found in N. pseudotrichia and has diverse biological activities. It is cytotoxic to BC-1 human breast cancer cells (IC50 = 5 µg/ml). Piloformic acid is active against L. braziliensis amastigotes (IC50 = 78.5 µM). It is also active against the plant pathogenic fungi C. gloeosporioides (MIC = 292 µM).

Chemical Structure

Piliformic Acid
Piliformic Acid
CAS#98985-76-3

Theoretical Analysis

MedKoo Cat#: 464343

Name: Piliformic Acid

CAS#: 98985-76-3

Chemical Formula: C11H18O4

Exact Mass: 214.1205

Molecular Weight: 214.26

Elemental Analysis: C, 61.66; H, 8.47; O, 29.87

Price and Availability

Size Price Availability Quantity
2mg USD 1,020.00 2 Weeks
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Related CAS #
No Data
Synonym
Piliformic Acid;
IUPAC/Chemical Name
(E)-2-hexylidene-3-methylsuccinic acid
InChi Key
YTUQECDNJQCQAE-VQHVLOKHSA-N
InChi Code
InChI=1S/C11H18O4/c1-3-4-5-6-7-9(11(14)15)8(2)10(12)13/h7-8H,3-6H2,1-2H3,(H,12,13)(H,14,15)/b9-7+
SMILES Code
OC(C(/C(C(O)=O)=C\CCCCC)C)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Piliformic acid is a fungal metabolite found in the endophytic fungus Xylariasp sp.(No. 2508) from mangrove trees from the coast of the South China Sea.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 214.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Sonyot W, Lamlertthon S, Luangsa-Ard JJ, Mongkolsamrit S, Usuwanthim K, Ingkaninan K, Waranuch N, Suphrom N. In Vitro Antibacterial and Anti- Inflammatory Effects of Novel Insect Fungus Polycephalomyces phaothaiensis Extract and Its Constituents against Propionibacterium acnes. Antibiotics (Basel). 2020 May 25;9(5):274. doi: 10.3390/antibiotics9050274. PMID: 32466146; PMCID: PMC7277416. 2: Elias LM, Fortkamp D, Sartori SB, Ferreira MC, Gomes LH, Azevedo JL, Montoya QV, Rodrigues A, Ferreira AG, Lira SP. The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose. Braz J Microbiol. 2018 Oct-Dec;49(4):840-847. doi: 10.1016/j.bjm.2018.03.003. Epub 2018 Mar 31. PMID: 29631892; PMCID: PMC6175768. 3: Cota BB, Tunes LG, Maia DNB, Ramos JP, Oliveira DM, Kohlhoff M, Alves TMA, Souza-Fagundes EM, Campos FF, Zani CL. Leishmanicidal compounds of Nectria pseudotrichia, an endophytic fungus isolated from the plant Caesalpinia echinata (Brazilwood). Mem Inst Oswaldo Cruz. 2018 Feb;113(2):102-110. doi: 10.1590/0074-02760170217. PMID: 29236928; PMCID: PMC5722265.