MedKoo Cat#: 464335 | Name: Nanangenine C
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nanangenine C is a drimane sesquiterpene that has been found in Aspergillus. It is active against B. subtilis (IC50 = 5.7 µg/ml) and cytotoxic to NS-1 mouse myeloma cells (IC50 = 4.1 µg/ml).

Chemical Structure

Nanangenine C
Nanangenine C
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 464335

Name: Nanangenine C

CAS#: unknown

Chemical Formula: C21H32O5

Exact Mass: 364.2250

Molecular Weight: 364.48

Elemental Analysis: C, 69.20; H, 8.85; O, 21.95

Price and Availability

Size Price Availability Quantity
1mg USD 550.00 2 Weeks
5mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
Nanangenine C; Nanangenine-C;
IUPAC/Chemical Name
(5R,5aS,9aS,9bS)-9b-hydroxy-6,6,9a-trimethyl-1-oxo-1,3,5,5a,6,7,8,9,9a,9b-decahydronaphtho[1,2-c]furan-5-yl hexanoate
InChi Key
ROECGAWNHRGIRN-GWKIZSTFSA-N
InChi Code
InChI=1S/C21H32O5/c1-5-6-7-9-16(22)26-15-12-14-13-25-18(23)21(14,24)20(4)11-8-10-19(2,3)17(15)20/h12,15,17,24H,5-11,13H2,1-4H3/t15-,17+,20+,21+/m1/s1
SMILES Code
CC1(CCC[C@]2([C@]1([C@@H](C=C([C@@]23O)COC3=O)OC(CCCCC)=O)[H])C)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Nanangenine C is a drimane sesquiterpene that is active against B. subtilis (IC50 = 5.7 µg/ml) and cytotoxic to NS-1 mouse myeloma cells (IC50 = 4.1 µg/ml).
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 364.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Lacey HJ, Gilchrist CLM, Crombie A, Kalaitzis JA, Vuong D, Rutledge PJ, Turner P, Pitt JI, Lacey E, Chooi YH, Piggott AM. Nanangenines: drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensis. Beilstein J Org Chem. 2019 Nov 5;15:2631-2643. doi: 10.3762/bjoc.15.256. PMID: 31807198; PMCID: PMC6880815.