Synonym
Diabeton; Glyklaside; 5-Hydroxyanthranilic acid
IUPAC/Chemical Name
Benzoic acid, 2-amino-5-hydroxy-
InChi Key
HYNQTSZBTIOFKH-UHFFFAOYSA-N
InChi Code
InChI=1S/C7H7NO3/c8-6-2-1-4(9)3-5(6)7(10)11/h1-3,9H,8H2,(H,10,11)
SMILES Code
O=C(O)C1=CC(O)=CC=C1N
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
153.14
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Shishkova VN. [Clinical significance of the ADVANCE study for a practitioner: Possibility to treat and prevent complications of type 2 diabetes mellitus]. Probl Endokrinol (Mosk). 2009 Oct 15;55(5):6-9. Russian. doi: 10.14341/probl20095556-9. PMID: 31569846.
2: Buĭdina TA, Kozlov GS, Balabolkin MI. Vliianie diabetona i metformina na protsessy svobodnoradikal'nogo okisleniia i strukturnye osobennosti fosfolipidnogo sostava éritrotsitarnykh membran pri insulinnezavisimom sakharnom diabete [The effect of diabeton and metformin on the free-radical oxidation processes and the structural characteristics of the phospholipid composition of the erythrocyte membranes in non-insulin-dependent diabetes mellitus]. Sov Med. 1991;(7):14-6. Russian. PMID: 1948331.
3: Pan'kiv VI. Primenenie diabetona u bol'nykh s nachal'nymi formami sakharnogo diabeta [Use of diabeton in patients with initial forms of diabetes mellitus]. Vrach Delo. 1986 Aug;(8):67-9. Russian. PMID: 3776165.
4: Velikov VK, Saltykov BB, Galkina AK, Kabaeva EV, Frolova AI, Privalova EV, Savina TS, Zelenchuk NM, Shubina OI, Iarovaia LD, et al. Effektivnost' antiagregantov--tiklida i diabetona v korrektsii khronicheskogo vnutrisosudistogo mikrosvertyvaniia krovi u bol'nykh sakharnym diabetom [The efficacy of the antiaggregants ticlid and diabeton in correcting chronic intravascular microcoagulation of the blood in diabetic patients]. Ter Arkh. 1991;63(10):44-9. Russian. PMID: 1805420.
5: Kashirina EP, Bryzgalina SM, Balabolkin MI. Diabeton v lechenii I stadii nefroangiopatii pri insulinzavisimom sakharnom diabete [Diabeton in the treatment of stage I nephroangiopathy in insulin-dependent diabetes mellitus]. Sov Med. 1991;(1):68-9. Russian. PMID: 1862390.
6: Dreval' AV, Kovachev BP, Misnikova IV, Kovaleva YA, Dreval' OA. [Study of new capacities in the evaluation of glycemic control in patients with type 2 diabetes]. Probl Endokrinol (Mosk). 2009 Apr 15;55(2):35-40. Russian. doi: 10.14341/probl200955235-40. PMID: 31569899.
7: Nedosugova LV, Lankin VZ, Reznik SM, Balabolkin MI, Antonova KV, Arzamastseva NE, Konovalova GG. [Effect of metformin on the magnitude of oxidative stress in patients with type 2 diabetes mellitus]. Probl Endokrinol (Mosk). 2007 Feb 15;53(1):3-7. Russian. doi: 10.14341/probl20075313-7. PMID: 31627622.
8: Kozlov GS, Buĭdina TA, Balabolkin MI. Lipidnyĭ spektr éritrotsitarnoĭ membrany pri razlichnykh vidakh sakharosnizhaiushcheĭ terapii [Spectrum of erythrocyte membrane lipids in various types of hypoglycemic therapy]. Sov Med. 1990;(6):10-3. Russian. PMID: 2396109.
9: Orlenko VL. [COMBINED HONDROPROTECTION IN REHABILITATION OF PATIENTS WITH DIABETES MELLITUS WITH DIABETIC ARTHROPATHY]. Lik Sprava. 2015 Jan- Mar;(1-2):102-8. Ukrainian. PMID: 26118037.
