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MedKoo Cat#: 413643 | Name: DF 594

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DF 594 is an antispasmodic that shows low affinity for neuronal M1 and heart M2 muscarinic receptors and high affinity for intestinal smooth muscle muscarinic receptors.

Chemical Structure

DF 594
DF 594
CAS#121798-89-8

Theoretical Analysis

MedKoo Cat#: 413643

Name: DF 594

CAS#: 121798-89-8

Chemical Formula: C19H21ClN4O2

Exact Mass: 372.1353

Molecular Weight: 372.85

Elemental Analysis: C, 61.21; H, 5.68; Cl, 9.51; N, 15.03; O, 8.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
DF 594; DF594; DF-594
IUPAC/Chemical Name
5H-Pyrido(2,3-b)(1,5)benzodiazepin-5-one, 6,11-dihydro-11-((1-methyl-3-piperidinyl)carbonyl)-, monohydrochloride
InChi Key
OSLNWPFLHSLBPY-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H20N4O2.ClH/c1-22-11-5-6-13(12-22)19(25)23-16-9-3-2-8-15(16)21-18(24)14-7-4-10-20-17(14)23;/h2-4,7-10,13H,5-6,11-12H2,1H3,(H,21,24);1H
SMILES Code
O=C1C2=CC=CN=C2N(C(C3CN(C)CCC3)=O)C4=CC=CC=C4N1.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 372.85 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: De Ponti F, Ambrosoli L, Borsa M, D'Angelo L, Frigo GM, Crema A. Inhibitory effects of DF 594, a new antispasmodic agent, on intestinal motility in the dog. Pharmacology. 1989;38(6):374-80. doi: 10.1159/000138560. PMID: 2813498. 2: Barocelli E, Morini G, Ballabeni V, Lavezzo A, Impicciatore M. Effects of two new pirenzepine analogs on the contractile response of the guinea-pig oesophageal muscularis mucosae to acetylcholine, bethanechol, histamine and high potassium. Eur J Pharmacol. 1990 Apr 10;179(1-2):89-96. doi: 10.1016/0014-2999(90)90405-u. PMID: 1973103. 3: Cosentino M, De Ponti F, D'Angelo L, Crema A. Motility of rabbit proximal colon. Relevance of cholinergic pathways and role of different muscarinic receptor subtypes. Dig Dis Sci. 1992 Nov;37(11):1746-53. doi: 10.1007/BF01299869. PMID: 1425075.

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