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MedKoo Cat#: 576269 | Name: BQ-610

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BQ-610 is an Endothelin A receptor antagonist.

Chemical Structure

BQ-610
BQ-610
CAS#141595-53-1

Theoretical Analysis

MedKoo Cat#: 576269

Name: BQ-610

CAS#: 141595-53-1

Chemical Formula: C36H44N6O6

Exact Mass: 656.3322

Molecular Weight: 656.78

Elemental Analysis: C, 65.84; H, 6.75; N, 12.80; O, 14.62

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
BQ 610; BQ610; BQ-610
IUPAC/Chemical Name
D-Tryptophan, N-(1-formyl-N-(N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl)-D-tryptophyl)-
InChi Key
QHSRPPJQBFQWSC-OJDZSJEKSA-N
InChi Code
InChI=1S/C36H44N6O6/c1-23(2)17-29(40-36(48)41-15-9-3-4-10-16-41)33(44)38-30(19-25-21-42(22-43)32-14-8-6-12-27(25)32)34(45)39-31(35(46)47)18-24-20-37-28-13-7-5-11-26(24)28/h5-8,11-14,20-23,29-31,37H,3-4,9-10,15-19H2,1-2H3,(H,38,44)(H,39,45)(H,40,48)(H,46,47)/t29-,30+,31+/m0/s1
SMILES Code
CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc2cn(C=O)c3ccccc23)C(=O)N[C@H](Cc4c[nH]c5ccccc45)C(=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 656.78 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Cirak B, Kiymaz N, Ari HH, Ugras S. The effects of endothelin antagonist BQ-610 on cerebral vascular wall following experimental subarachnoid hemorrhage and cerebral vasospasm. Clin Auton Res. 2004 Jun;14(3):197-201. doi: 10.1007/s10286-004-0190-2. PMID: 15241650. 2. Beyer ME, Slesak G, Hövelborn T, Kazmaier S, Nerz S, Hoffmeister HM. Inotropic effects of endothelin-1: interaction with molsidomine and with BQ 610. Hypertension. 1999 Jan;33(1):145-52. doi: 10.1161/01.hyp.33.1.145. PMID: 9931095.