MC-Gly-Gly-Phe | CAS#1599440-15-9 | ADC cleavable linker

MedKoo Cat#: 555936 | Name: MC-Gly-Gly-Phe

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).

Chemical Structure

MC-Gly-Gly-Phe

CAS#1599440-15-9

Theoretical Analysis

MedKoo Cat#: 555936

Name: MC-Gly-Gly-Phe

CAS#: 1599440-15-9

Chemical Formula: C23H28N4O7

Exact Mass: 472.1958

Molecular Weight: 472.50

Elemental Analysis: C, 58.47; H, 5.97; N, 11.86; O, 23.70

Price and Availability

Size	Price	Availability
50mg	USD 450.00	2 Weeks
100mg	USD 750.00	2 Weeks
200mg	USD 1,250.00	2 Weeks
500mg	USD 2,650.00	2 Weeks
1g	USD 3,850.00	2 Weeks

Bulk Inquiry

Buy Now

Add to Cart

Related CAS #

No Data

Synonym

MC-Gly-Gly-Phe; MC Gly-Gly-Phe; MC-Gly-Gly Phe

IUPAC/Chemical Name

(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl)glycylglycyl-L-phenylalanine

InChi Key

NFVPAFLSJIPUCL-KRWDZBQOSA-N

InChi Code

InChI=1S/C23H28N4O7/c28-18(9-5-2-6-12-27-21(31)10-11-22(27)32)24-14-19(29)25-15-20(30)26-17(23(33)34)13-16-7-3-1-4-8-16/h1,3-4,7-8,10-11,17H,2,5-6,9,12-15H2,(H,24,28)(H,25,29)(H,26,30)(H,33,34)/t17-/m0/s1

SMILES Code

O=C(O)[C@H](CC1=CC=CC=C1)NC(CNC(CNC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Product Data

Product Data

Instruction

View handling instruction

Biological target:

MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).

In vitro activity:

TBD

In vivo activity:

TBD

	Solvent	mg/mL	mM
Solubility
	DMSO	50.0	105.82

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 472.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.