MedKoo Cat#: 555935 | Name: Boc-Gly-Gly-Phe-Gly-OH
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Boc-Gly-Gly-Phe-Gly-OH is a protease cleavable linker used for the antibody-drug conjugate (ADC).

Chemical Structure

Boc-Gly-Gly-Phe-Gly-OH
Boc-Gly-Gly-Phe-Gly-OH
CAS#187794-49-6

Theoretical Analysis

MedKoo Cat#: 555935

Name: Boc-Gly-Gly-Phe-Gly-OH

CAS#: 187794-49-6

Chemical Formula: C20H28N4O7

Exact Mass: 436.1958

Molecular Weight: 436.47

Elemental Analysis: C, 55.04; H, 6.47; N, 12.84; O, 25.66

Price and Availability

Size Price Availability Quantity
100mg USD 350.00 2 Weeks
200mg USD 550.00 2 Weeks
500mg USD 950.00 2 Weeks
1g USD 1,450.00 2 Weeks
2g USD 2,250.00 2 Weeks
5g USD 4,250.00 2 Weeks
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Related CAS #
No Data
Synonym
Boc-Gly-Gly-Phe-Gly-OH;
IUPAC/Chemical Name
(tert-butoxycarbonyl)glycylglycyl-L-phenylalanylglycine
InChi Key
PTUJJIPXBJJLLV-AWEZNQCLSA-N
InChi Code
InChI=1S/C20H28N4O7/c1-20(2,3)31-19(30)23-10-15(25)21-11-16(26)24-14(18(29)22-12-17(27)28)9-13-7-5-4-6-8-13/h4-8,14H,9-12H2,1-3H3,(H,21,25)(H,22,29)(H,23,30)(H,24,26)(H,27,28)/t14-/m0/s1
SMILES Code
O=C(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(O)=O)=O)=O)CNC(OC(C)(C)C)=O
Appearance
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 436.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
[1]. Antibody-drug conjugate. WO2014057687A1. https://patents.google.com/patent/WO2014057687A1/en