MedKoo Cat#: 464291 | Name: Dioxacarb

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dioxacarb is a carbamate pesticide. Carbamate pesticides are derived from carbamic acid and kill insects in a similar fashion as organophosphate insecticides. They are widely used in homes, gardens and agriculture.

Chemical Structure

Dioxacarb
Dioxacarb
CAS#6988-21-2

Theoretical Analysis

MedKoo Cat#: 464291

Name: Dioxacarb

CAS#: 6988-21-2

Chemical Formula: C11H13NO4

Exact Mass: 223.0845

Molecular Weight: 223.23

Elemental Analysis: C, 59.19; H, 5.87; N, 6.27; O, 28.67

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Dioxacarb; Dioxacarbe; Elocron; NSC 190981; NSC190981; NSC-190981;
IUPAC/Chemical Name
2-(1,3-dioxolan-2-yl)phenyl methylcarbamate
InChi Key
SDKQRNRRDYRQKY-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H13NO4/c1-12-11(13)16-9-5-3-2-4-8(9)10-14-6-7-15-10/h2-5,10H,6-7H2,1H3,(H,12,13)
SMILES Code
CNC(Oc1c(C2OCCO2)cccc1)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 223.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Růžičková J, Raclavská H, Kucbel M, Grobelak A, Šafář M, Raclavský K, Švédová B, Juchelková D, Moustakas K. The potential environmental risks of the utilization of composts from household food waste. Environ Sci Pollut Res Int. 2020 Jul 23. doi: 10.1007/s11356-020-09916-5. Epub ahead of print. PMID: 32705551. 2: Ristau K, Akgül Y, Bartel AS, Fremming J, Müller MT, Reiher L, Stapela F, Splett JP, Spann N. Toxicity in relation to mode of action for the nematode Caenorhabditis elegans: Acute-to-chronic ratios and quantitative structure- activity relationships. Environ Toxicol Chem. 2015 Oct;34(10):2347-53. doi: 10.1002/etc.3069. Epub 2015 Sep 11. PMID: 25994998. 3: Eren Y, Erdoğmuş SF, Akyıl D, Özkara A, Konuk M, Sağlam E. Cytotoxic and genotoxic effects of dioxacarb by human peripheral blood lymphocytes CAs and Allium test. Cytotechnology. 2015 Dec;67(6):1023-30. doi: 10.1007/s10616-014-9741-0. Epub 2014 May 22. PMID: 24848210; PMCID: PMC4628927. 4: Wang L, Zhou Y, Huang X, Wang R, Lin Z, Chen Y, Wang D, Lin D, Xu D. [Determination of 51 carbamate pesticide residues in vegetables by liquid chromatography-tandem mass spectrometry based on optimization of QuEChERS sample preparation method]. Se Pu. 2013 Dec;31(12):1167-75. Chinese. doi: 10.3724/sp.j.1123.2013.05051. PMID: 24669707. 5: Morrica P, Fidente P, Seccia S. Liquid chromatographic determination of nine N-methylcarbamates in drinking water. Biomed Chromatogr. 2005 Jan;19(1):107-10. doi: 10.1002/bmc.426. PMID: 15470700. 6: Wang Q, Lemley AT. Competitive degradation and detoxification of carbamate insecticides by membrane anodic Fenton treatment. J Agric Food Chem. 2003 Aug 27;51(18):5382-90. doi: 10.1021/jf034311f. PMID: 12926887. 7: Caballo-López A, Luque de Castro MD. Continuous ultrasound-assisted extraction coupled to on line filtration-solid-phase extraction-column liquid chromatography--post column derivatisation-fluorescence detection for the determination of N-methylcarbamates in soil and food. J Chromatogr A. 2003 May 23;998(1-2):51-9. doi: 10.1016/s0021-9673(03)00646-0. PMID: 12862371. 8: Gecheva G. Resistance of the German cockroach Blattella germanica (L.) to dioxacarb in Bulgaria. Appl Parasitol. 1993 Nov;34(4):295-8. PMID: 8298663. 9: Ali MS, White JD, Bakowski RS, Phillippo ET, Ellis RL. Analyte stability study of N-methylcarbamate pesticides in beef and poultry liver tissues by liquid chromatography. J AOAC Int. 1993 Nov-Dec;76(6):1309-16. PMID: 8286970. 10: Kokshareva NV. Terapevticheskaia éffektivnost' alloksima pri éksperimental'noĭ intoksikatsii karbaminovymi pestitsidami [The therapeutic efficacy of alloxime in experimental carbamate pesticide poisoning]. Eksp Klin Farmakol. 1992 Nov-Dec;55(6):51-3. Russian. PMID: 1305879. 11: Wegner Z, Stańczak J, Okróy-Rysop G. Badania doświadczalne nad redukcja komarów z rodzaju Anopheles przy zastosowaniu wybranych insektycydów [Experimental studies of the control of mosquitoes of the genus Anopheles using selected insecticides]. Wiad Parazytol. 1991;37(1):179-83. Polish. PMID: 1823486. 12: Kokshareva NV, Badaeva LN. Strukturno-funktsional'nye izmeneniia v razlichnykh otdelakh golovnogo i spinnogo mozga pri vozdeĭstvii dioksakarbom [Structural-functional changes in different sections of the brain and spinal cord exposed to dioxacarb]. Fiziol Zh. 1988 May-Jun;34(3):27-32. Russian. PMID: 3410113. 13: Racewicz M. Detection of the resistance in cockroaches Blattella germanica (L.) from ships to insecticides used. Bull Inst Marit Trop Med Gdynia. 1986;37(3-4):255-61. PMID: 3125873. 14: Krause RT. Liquid chromatographic determination of N-methylcarbamate insecticides and metabolites in crops. II. Analytical characteristics and residue findings. J Assoc Off Anal Chem. 1985 Jul-Aug;68(4):734-41. PMID: 4030646. 15: Drevenkar V, Stengl B, Tkalcević B, Vasilić Z. Occupational exposure control by simultaneous determination of N-methylcarbamates and organophosphorus pesticide residues in human urine. Int J Environ Anal Chem. 1983;14(3):215-30. doi: 10.1080/03067318308071621. PMID: 6853013. 16: Rettich F. Residual toxicity of wall-sprayed organophosphates, carbamates and pyrethroids to mosquito Culex pipiens molestus Forskal. J Hyg Epidemiol Microbiol Immunol. 1980;24(1):110-7. PMID: 7190586. 17: Bosković B, Vojvodić V, Maksimović M, Granov A, Besarović-Lazarev S, Binenfeld Z. Effect of mono- and bis-quaternary pyridinium oximes on the acute toxicity and on the serumcholinesterase inhibitory activity of dioxacarb, carbaryl and carbofuran. Arh Hig Rada Toksikol. 1976;27(4):289-95. PMID: 828041.