MedKoo Cat#: 413542 | Name: Deposiston

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Deposiston is an estrogen medication which has been used in birth control pills for women and in the treatment of prostate cancer in men. It has also been investigated in the treatment of breast cancer in women. The medication was combined with norethisterone acetate in birth control pills. EES is taken by mouth once per week.

Chemical Structure

Deposiston
Deposiston
CAS#54958-72-4

Theoretical Analysis

MedKoo Cat#: 413542

Name: Deposiston

CAS#: 54958-72-4

Chemical Formula: C45H58O7S

Exact Mass: 742.3903

Molecular Weight: 743.01

Elemental Analysis: C, 72.74; H, 7.87; O, 15.07; S, 4.31

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Deposiston
IUPAC/Chemical Name
(8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate compound with (8R,9S,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl propane-2-sulfonate (1:1)
InChi Key
GBBLXLZDAKZQGW-XOCSYMDRSA-N
InChi Code
InChI=1S/C23H30O4S.C22H28O3/c1-5-23(24)13-11-21-20-8-6-16-14-17(27-28(25,26)15(2)3)7-9-18(16)19(20)10-12-22(21,23)4;1-4-22(25-14(2)23)12-10-20-19-7-5-15-13-16(24)6-8-17(15)18(19)9-11-21(20,22)3/h1,7,9,14-15,19-21,24H,6,8,10-13H2,2-4H3;1,13,17-20H,5-12H2,2-3H3/t19-,20-,21+,22+,23+;17-,18+,19+,20-,21-,22-/m10/s1
SMILES Code
CC(S(=O)(Oc1cc2c([C@H]3CC[C@]4([C@H]([C@@H]3CC2)CC[C@]4(C#C)O)C)cc1)=O)C.CC(O[C@@]5(C#C)CC[C@H]6[C@@H]7CCC8=CC(CC[C@@H]8[C@H]7CC[C@]56C)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 743.01 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Vasilev D. Khormonalna kontratseptsiia s pomoshtta na oralen depo-preparat Deposiston [Hormonal contraception using the oral depot preparation, Deposiston]. Akush Ginekol (Sofiia). 1978;17(2):147-51. Bulgarian. PMID: 350070. 2: Meyer FP, Canzler E, Giers H, Walther H. Zeitverlauf der Hemmung der Coffeinelimination unter dem Einfluss des oralen Depotkontrazeptivum Deposiston. Hormonale Kontrazeptiva und Coffeinelimination [Time course of inhibition of caffeine elimination in response to the oral depot contraceptive agent Deposiston. Hormonal contraceptives and caffeine elimination]. Zentralbl Gynakol. 1991;113(6):297-302. German. PMID: 2058339. 3: Ludwig C, Arnold M, Ludwig A. Klinische, microbiologische und zytologische Veränderungen an der Gingiva unter dem Einfluss von "Deposiston" [Clinical, microbiological and cytological changes in the gingiva as affected by Deposiston]. Zahn Mund Kieferheilkd Zentralbl. 1983;71(6):587-94. German. PMID: 6229106. 4: Gruhn K, Hennig A, Klinger G, Krause G. Einfluss von Kontrazeptiva auf die Verdaulichkeit des Nahrungsproteins und die N-Bilanz [Effect of contraceptives on the digestibility of dietary protein and nitrogen balance]. Nahrung. 1981;25(8):779-88. German. doi: 10.1002/food.19810250811. PMID: 7290175. 5: Richter J, Heine W, Rudolf K, Uhlmann M. Intravenöser Insulinbelastungstest und Wachsdtumshormonsekretion bei Mädchen mit konstitutionell-hereditärem Hochwuchs vor und während der Behandlung mit Deposiston [Continuous intravenous infusion of insulin to girls with hereditary tall growth and secretion of human growth hormone, prior to and during Deposiston treatment (author's transl)]. Zentralbl Gynakol. 1980;102(19):1117-20. German. PMID: 7008461. 6: Frick G, Göretzlehner G. Veränderungen der Heparinozyten unter der Einnahme von Deposiston und Sequenz-Ovosiston [Changes in heparinocytes during the administration of Depositon and Sequenz-Ovosiston]. Zentralbl Gynakol. 1975;97(8):488-93. German. PMID: 56830. 7: Brügmann E, Göretzlehner G, Töwe J, Rehpenning W. Leberfunktionsuntersuchungen nach sechsmonatiger Einnahme von Deposiston [Liver function tests after a 6-month deposiston therapy]. Zentralbl Gynakol. 1975;97(11):669-73. German. PMID: 1189758. 8: Nischan P, Ebeling K, Thomas DB, Hirsch U. Comparison of recalled and validated oral contraceptive histories. Am J Epidemiol. 1993 Nov 1;138(9):697-703. doi: 10.1093/oxfordjournals.aje.a116907. PMID: 8237985. 9: Klinger G, Gruhn K. Aminosäuren im Speichel [Amino acids in saliva]. Zahn Mund Kieferheilkd Zentralbl. 1984;72(7):651-6. German. PMID: 6240853. 10: Branczeisz J, Hubl W, Freymann E, Sarembe B. Zur Wirkung von Deposiston auf die Hormonsekretion des Renin-Aldosteron-Systems, der Nebennierenrinde und des Hypophyse-Ovar-Systems [Effect of Deposiston on hormone secretion of the renin- aldosterone system, the adrenal cortex and the pituitary - ovary system]. Z Arztl Fortbild (Jena). 1983;77(3):109-11. German. PMID: 6344451.