Kinetensin is a nonapeptide that has been found in pepsin-treated human plasma. It binds to neurotensin receptors in HT-29 cells and mouse brain (Kis = 1,396 and 149.6 nM, respectively, in radioligand binding assays) but does not induce the accumulation of intracellular calcium in HT-29 cells (EC50 = >10,000 nM). It induces histamine release in isolated rat peritoneal mast cells with an EC50 value of approximately 10 µM. Intradermal administration of kinetensin induces vascular permeability in rats.
MedKoo Cat#: 464183
Name: Kinetensin TFA salt
CAS#: unknown
Chemical Formula: C58H86F3N17O13
Exact Mass:
Molecular Weight: 1286.43
Elemental Analysis: C, 54.15; H, 6.74; F, 4.43; N, 18.51; O, 16.17
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| To be determined | 0.0 | 100.00 |
The following data is based on the product molecular weight 1,286.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
