MedKoo Cat#: 576131 | Name: Omeprazole magnesium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Omeprazole magnesium is a medication used in the treatment of gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. Omeprazole is a proton pump inhibitor and as such blocks the release of stomach acid.

Chemical Structure

Omeprazole magnesium
Omeprazole magnesium
CAS#95382-33-5

Theoretical Analysis

MedKoo Cat#: 576131

Name: Omeprazole magnesium

CAS#: 95382-33-5

Chemical Formula: C34H36MgN6O6S2

Exact Mass: 712.1988

Molecular Weight: 713.12

Elemental Analysis: C, 57.27; H, 5.09; Mg, 3.41; N, 11.79; O, 13.46; S, 8.99

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
H 168/68 magnesium; Omeprazole magnesium
IUPAC/Chemical Name
magnesium 5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide
InChi Key
KWORUUGOSLYAGD-UHFFFAOYSA-N
InChi Code
InChI=1S/2C17H18N3O3S.Mg/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h2*5-8H,9H2,1-4H3;/q2*-1;+2
SMILES Code
[Mg+2].COc1ccc2[n-]c(nc2c1)[S+]([O-])Cc3ncc(C)c(OC)c3C.COc4ccc5[n-]c(nc5c4)[S+]([O-])Cc6ncc(C)c(OC)c6C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Solvent mg/mL mM
Solubility
Soluble in DMSO 0.0 100.00
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 713.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Banihani SA. Omeprazole and Semen Quality. Basic Clin Pharmacol Toxicol. 2016 Mar;118(3):181-3. doi: 10.1111/bcpt.12529. Epub 2015 Dec 28. Review. PubMed PMID: 26572503. 2: Qi Q, Wang R, Liu L, Zhao F, Wang S. Comparative effectiveness and tolerability of esomeprazole and omeprazole in gastro-esophageal reflux disease: A systematic review and meta-analysis. Int J Clin Pharmacol Ther. 2015 Oct;53(10):803-10. doi: 10.5414/CP202396. Review. PubMed PMID: 26329348. 3: Akinseye OA, Alfishawy M, Radparvar F, Bakshi S. Trazodone and omeprazole interaction causing frequent second-degree Mobitz type 1 atrioventricular (AV) block (Wenckebach phenomenon) and syncope: a case report and literature review. Am J Case Rep. 2015 May 27;16:319-21. doi: 10.12659/AJCR.893427. Review. PubMed PMID: 26017199; PubMed Central PMCID: PMC4456984. 4: Bliden KP, Brener M, Gesheff MG, Franzese CJ, Tabrizchi A, Tantry U, Gurbel PA. PA tablets: investigational compounds combining aspirin and omeprazole for cardioprotection. Future Cardiol. 2013 Nov;9(6):785-97. doi: 10.2217/fca.13.67. Review. PubMed PMID: 24180537. 5: Gandi P, Vasireddi SR, Gurram SR, Darasani K. Evaluation of the Antibacterial efficacy of Omeprazole with Sodium Hypochlorite as an Endodontic Irrigating Solution- An Invivo Study. J Int Oral Health. 2013 Apr;5(2):14-20. Review. PubMed PMID: 24155586; PubMed Central PMCID: PMC3768071.