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MedKoo Cat#: 464149 | Name: Antileishmanial-24c

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Antileishmanial-24c is a novel antileishmanial agent, strongly inhibiting recombinant CYP51 from L. donovani, displaying activity against L. donovani intracellular amastigotes with an IC50 value of 0.53 μM.

Chemical Structure

Antileishmanial-24c
Antileishmanial-24c
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 464149

Name: Antileishmanial-24c

CAS#: unknown

Chemical Formula: C26H35N5O2

Exact Mass: 449.2791

Molecular Weight: 449.60

Elemental Analysis: C, 69.46; H, 7.85; N, 15.58; O, 7.12

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Antileishmanial-24c; Antileishmanial 24c;
IUPAC/Chemical Name
N-(4-((8-(1H-imidazol-1-yl)octyl)oxy)-2-isopropoxyphenyl)picolinimidamide
InChi Key
NCANPBPLGGDYJC-UHFFFAOYSA-N
InChi Code
InChI=1S/C26H35N5O2/c1-21(2)33-25-19-22(12-13-23(25)30-26(27)24-11-7-8-14-29-24)32-18-10-6-4-3-5-9-16-31-17-15-28-20-31/h7-8,11-15,17,19-21H,3-6,9-10,16,18H2,1-2H3,(H2,27,30)
SMILES Code
N=C(NC1=CC=C(OCCCCCCCCN2C=CN=C2)C=C1OC(C)C)C3=NC=CC=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Solvent mg/mL mM comments
Solubility
Soluble in DMSO 0.0 100.00
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 449.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL