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MedKoo Cat#: 413424 | Name: Cyenopyrafen

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cyenopyrafen is an acaricide.

Chemical Structure

Cyenopyrafen
Cyenopyrafen
CAS#560121-52-0

Theoretical Analysis

MedKoo Cat#: 413424

Name: Cyenopyrafen

CAS#: 560121-52-0

Chemical Formula: C13H13F4N5O3S2

Exact Mass: 427.0396

Molecular Weight: 427.39

Elemental Analysis: C, 36.53; H, 3.07; F, 17.78; N, 16.39; O, 11.23; S, 15.00

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Cyenopyrafen
IUPAC/Chemical Name
4-(4,5-dihydro-4-methyl-5-oxo-3-(trifluoromethyl)-1H-1,2,4-triazol-1-yl)-2-((ethylsulfonyl)amino)-5-fluorobenzenecarbothioamide
InChi Key
LVKBXDHACCFCTA-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H13F4N5O3S2/c1-3-27(24,25)20-8-5-9(7(14)4-6(8)10(18)26)22-12(23)21(2)11(19-22)13(15,16)17/h4-5,20H,3H2,1-2H3,(H2,18,26)
SMILES Code
S=C(C1=CC(F)=C(N2N=C(C(F)(F)F)N(C)C2=O)C=C1NS(=O)(CC)=O)N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Solvent mg/mL mM
Solubility
Soluble in DMSO 0.0 100.00
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 427.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Khalighi M, Dermauw W, Wybouw N, Bajda S, Osakabe M, Tirry L, Van Leeuwen T. Molecular analysis of cyenopyrafen resistance in the two-spotted spider mite Tetranychus urticae. Pest Manag Sci. 2016 Jan;72(1):103-12. doi: 10.1002/ps.4071. Epub 2015 Aug 10. PMID: 26118668. 2: Chen JC, Gong YJ, Shi P, Wang ZH, Cao LJ, Wang P, Wei SJ. Field-evolved resistance and cross-resistance of the two-spotted spider mite, Tetranychus urticae, to bifenazate, cyenopyrafen and SYP-9625. Exp Appl Acarol. 2019 Apr;77(4):545-554. doi: 10.1007/s10493-019-00359-3. Epub 2019 Apr 17. PMID: 30997606. 3: Sugimoto N, Osakabe M. Cross-resistance between cyenopyrafen and pyridaben in the twospotted spider mite Tetranychus urticae (Acari: Tetranychidae). Pest Manag Sci. 2014 Jul;70(7):1090-6. doi: 10.1002/ps.3652. Epub 2013 Oct 13. PMID: 24030907. 4: Kabir MH, El-Aty AMA, Kim SW, Rahman MM, Chung HS, Lee HS, Shin HC, Shim JH. Decline pattern and risk assessment of cyenopyrafen in different varieties of Asian pear using liquid chromatography and tandem mass spectrometry. Food Sci Biotechnol. 2017 Apr 30;26(2):537-543. doi: 10.1007/s10068-017-0074-6. PMID: 30263576; PMCID: PMC6049445. 5: Riga M, Myridakis A, Tsakireli D, Morou E, Stephanou EG, Nauen R, Van Leeuwen T, Douris V, Vontas J. Functional characterization of the Tetranychus urticae CYP392A11, a cytochrome P450 that hydroxylates the METI acaricides cyenopyrafen and fenpyroximate. Insect Biochem Mol Biol. 2015 Oct;65:91-9. doi: 10.1016/j.ibmb.2015.09.004. Epub 2015 Sep 9. PMID: 26363294. 6: Sugimoto N, Takahashi A, Ihara R, Itoh Y, Jouraku A, Van Leeuwen T, Osakabe M. QTL mapping using microsatellite linkage reveals target-site mutations associated with high levels of resistance against three mitochondrial complex II inhibitors in Tetranychus urticae. Insect Biochem Mol Biol. 2020 Aug;123:103410. doi: 10.1016/j.ibmb.2020.103410. Epub 2020 May 19. PMID: 32442626. 7: Khalighi M, Tirry L, Van Leeuwen T. Cross-resistance risk of the novel complex II inhibitors cyenopyrafen and cyflumetofen in resistant strains of the two-spotted spider mite Tetranychus urticae. Pest Manag Sci. 2014 Mar;70(3):365-8. doi: 10.1002/ps.3641. Epub 2013 Oct 2. PMID: 23997025. 8: Papapostolou KM, Riga M, Charamis J, Skoufa E, Souchlas V, Ilias A, Dermauw W, Ioannidis P, Van Leeuwen T, Vontas J. Identification and characterization of striking multiple-insecticide resistance in a Tetranychus urticae field population from Greece. Pest Manag Sci. 2021 Feb;77(2):666-676. doi: 10.1002/ps.6136. Epub 2020 Nov 6. PMID: 33051974. 9: Yu H, Cheng Y, Xu M, Song Y, Luo Y, Li B. Synthesis, Acaricidal Activity, and Structure-Activity Relationships of Pyrazolyl Acrylonitrile Derivatives. J Agric Food Chem. 2016 Dec 28;64(51):9586-9591. doi: 10.1021/acs.jafc.6b04221. Epub 2016 Dec 15. PMID: 27976890. 10: Xu D, He Y, Zhang Y, Xie W, Wu Q, Wang S. Status of pesticide resistance and associated mutations in the two-spotted spider mite, Tetranychus urticae, in China. Pestic Biochem Physiol. 2018 Sep;150:89-96. doi: 10.1016/j.pestbp.2018.07.008. Epub 2018 Jul 19. PMID: 30195393.