MedKoo Cat#: 576042 | Name: GT-1061

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GT-1061 is a nitrate that may have therapeutic activity.

Chemical Structure

GT-1061
GT-1061
CAS#252568-49-3

Theoretical Analysis

MedKoo Cat#: 576042

Name: GT-1061

CAS#: 252568-49-3

Chemical Formula: C6H8N2O3S

Exact Mass: 188.0256

Molecular Weight: 188.20

Elemental Analysis: C, 38.29; H, 4.28; N, 14.89; O, 25.50; S, 17.03

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
GT-1061; GT1061; GT 1061
IUPAC/Chemical Name
4-Methyl-5-(2-nitrooxy-ethyl)-thiazole
InChi Key
SPXXSCWWBQGVLL-UHFFFAOYSA-N
InChi Code
InChI=1S/C6H8N2O3S/c1-5-6(12-4-7-5)2-3-11-8(9)10/h4H,2-3H2,1H3
SMILES Code
Cc1ncsc1CCO[N+](=O)[O-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Solvent mg/mL mM
Solubility
Soluble in DMSO 0.0 100.00
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 188.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Beninger RJ, Forsyth JK, Van Adel M, Reynolds JN, Boegman RJ, Jhamandas K. Subchronic MK-801 behavioural deficits in rats: partial reversal by the novel nitrate GT 1061. Pharmacol Biochem Behav. 2009 Feb;91(4):495-502. doi: 10.1016/j.pbb.2008.09.003. Epub 2008 Sep 10. PMID: 18834899. 2. Thatcher GR, Bennett BM, Dringenberg HC, Reynolds JN. Novel nitrates as NO mimetics directed at Alzheimer's disease. J Alzheimers Dis. 2004 Dec;6(6 Suppl):S75-84. doi: 10.3233/jad-2004-6s614. PMID: 15665418.