Preterramide C is a fungal metabolite that has been found in A. terreus. It is active against S. aureus (MIC = 52.4 µM) but not E. aerogenes, P. aeruginosa, or C. albicans (MICs = >100 µM for all). Preterramide C inhibits the growth of L5178Y mouse lymphoma cells with an IC50 value of 0.1 µg/ml. It also inhibits nitric oxide (NO) production induced by LPS in RAW 264.7 cells (IC50 = 5.48 µM).
MedKoo Cat#: 464106
Name: Preterramide C
CAS#: 81469-77-4
Chemical Formula: C24H23N3O7
Exact Mass: 465.1536
Molecular Weight: 465.46
Elemental Analysis: C, 61.93; H, 4.98; N, 9.03; O, 24.06
| Solvent | mg/mL | mM | comments | |
|---|---|---|---|---|
| Solubility | ||||
| Soluble in DMSO | 0.0 | 100.00 |
The following data is based on the product molecular weight 465.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
