CP 17193 | CAS# 77617-75-5 | immunosuppressive pyrazaloquinoline

MedKoo Cat#: 413308 | Name: CP 17193

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CP 17193 is an immunosuppressive pyrazaloquinoline

Chemical Structure

CP 17193

CAS#77617-75-5

Theoretical Analysis

MedKoo Cat#: 413308

Name: CP 17193

CAS#: 77617-75-5

Chemical Formula: C16H11ClN2OS

Exact Mass: 314.0281

Molecular Weight: 314.79

Elemental Analysis: C, 61.05; H, 3.52; Cl, 11.26; N, 8.90; O, 5.08; S, 10.18

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

CP 17193; CP17,193; CP 17,193; CP-17,193

IUPAC/Chemical Name

(1)Benzothiopyrano(4,3-c)pyrazol-3(2H)-one, 2-(4-chlorophenyl)-1,4-dihydro-

InChi Key

JUINMUAIPTYUBI-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H11ClN2OS/c17-10-5-7-11(8-6-10)19-16(20)13-9-21-14-4-2-1-3-12(14)15(13)18-19/h1-8,18H,9H2

SMILES Code

O=C1C(CSC2=CC=CC=C23)=C3NN1C4=CC=C(Cl)C=C4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	Soluble in DMSO	0.0	100.00

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 314.79 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Bundick RV, Eady RP. The effects of CP 17193, an immunosuppressive pyrazaloquinoline, on the development of spontaneous lupus disease in NZBW F1 hybrid mice. Clin Exp Immunol. 1992 Aug;89(2):179-84. doi: 10.1111/j.1365-2249.1992.tb06929.x. PMID: 1638762; PMCID: PMC1554431. 2: Otterness IG. Comparative activity of CP-17,193 and five established immunosuppressives toward the antigens SRBC and EL4. Clin Exp Immunol. 1981 Nov;46(2):332-9. PMID: 7039885; PMCID: PMC1536394. 3: Otterness IG, Bliven ML. The mechanism of tumor allograft survival induced by CP-17,193. Immunopharmacology. 1982 Aug;4(4):341-54. doi: 10.1016/0162-3109(82)90055-8. PMID: 6981629. 4: Lombardino JG, Otterness IG. Novel immunosuppressive agents. Potent immunological activity of some bensothiopyrano [4,3-c]pyrazol-3-ones. J Med Chem. 1981 Jul;24(7):830-4. doi: 10.1021/jm00139a012. PMID: 7277388.