(±)-LY367385 | CAS#198419-90-8 | mGluR1α antagonist

MedKoo Cat#: 464005 | Name: (±)-LY367385

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(±)-LY367385 is an antagonist of metabotropic glutamate receptor 1α (mGluR1α). It inhibits phosphoinositide (PI) hydrolysis selectively in AV-12 cells expressing mGluR1α over those expressing mGluR5a.

Chemical Structure

(±)-LY367385

CAS#198419-90-8

Theoretical Analysis

MedKoo Cat#: 464005

Name: (±)-LY367385

CAS#: 198419-90-8

Chemical Formula: C10H11NO4

Exact Mass: 209.0688

Molecular Weight: 209.20

Elemental Analysis: C, 57.41; H, 5.30; N, 6.70; O, 30.59

Price and Availability

Size	Price	Availability	Quantity
5mg	USD 400.00	2 Weeks
10mg	USD 750.00	2 Weeks

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Related CAS #

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Synonym

(±)-LY367385; (±)-LY 367385; (±)-LY-367385; (±) LY 367385; (±) LY367385; (±) LY-367385; LY367385; LY 367385; LY-367385;

IUPAC/Chemical Name

4-(amino(carboxy)methyl)-3-methylbenzoic acid

InChi Key

SGIKDIUCJAUSRD-UHFFFAOYSA-N

InChi Code

InChI=1S/C10H11NO4/c1-5-4-6(9(12)13)2-3-7(5)8(11)10(14)15/h2-4,8H,11H2,1H3,(H,12,13)(H,14,15)

SMILES Code

OC(C(N)C1=C(C)C=C(C(O)=O)C=C1)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	Soluble in DMSO	0.0	100.00

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 209.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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