Synonym
Propiopromazine; BAY188; BAY-188; BAY 188
IUPAC/Chemical Name
1-(10-(3-(Dimethylamino)propyl)-10H-phenothiazin-2-yl)propan-1-one
InChi Key
ZQTVCQIJTREKSP-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H24N2OS/c1-4-18(23)15-10-11-20-17(14-15)22(13-7-12-21(2)3)16-8-5-6-9-19(16)24-20/h5-6,8-11,14H,4,7,12-13H2,1-3H3
SMILES Code
CCC(C(C=C1N2CCCN(C)C)=CC=C1SC3=C2C=CC=C3)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
|
Solvent |
mg/mL |
mM |
| Solubility |
| Soluble in DMSO |
0.0 |
100.00 |
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.
Preparing Stock Solutions
The following data is based on the
product
molecular weight
340.49
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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6: Olling M, Stephany RW, Rauws AG. The determination of propiopromazine in animal tissue. J Vet Pharmacol Ther. 1981 Dec;4(4):291-4. doi: 10.1111/j.1365-2885.1981.tb00865.x. PMID: 7349344.
7: Trombik P, Cieślik-Boczula K. Influence of phenothiazine molecules on the interactions between positively charged poly-l-lysine and negatively charged DPPC/DPPG membranes. Spectrochim Acta A Mol Biomol Spectrosc. 2020 Feb 15;227:117563. doi: 10.1016/j.saa.2019.117563. Epub 2019 Oct 12. PMID: 31689607.
8: Hofman WF, Riegle GD. Effects of electroanesthesia and a phenothiazine tranquilizer on thermoregulation in the sheep. Am J Vet Res. 1977 Mar;38(3):403-6. PMID: 15489.
9: Patricolo M, Paolocci N, Zangari A, Antonica A, Rossi L, Magni F, Viola-Magni MP, Caione P, Lais A, Rivosecchi M. Resezione epatica fetale nel coniglio. Confronto istologico della rigenerazione tissutale del feto e dell'adulto [Hepatic resection in the fetal rabbit. Histologic comparison of tissue regeneration in the fetus versus the adult]. Minerva Chir. 1996 Nov;51(11):971-7. Italian. PMID: 9072727.
10: Rauws AG. Tranquillizers bij transport van slachtvarkens: een residuprobleem? [Tranquilizers in the transport of slaughtering pigs: a problem of residues?]. Tijdschr Diergeneeskd. 1983 Sep 1;108(17):659-64. Dutch. PMID: 6138880.
