Synonym
Thimerosal; HSDB7151; HSDB-7151; HSDB 7151
IUPAC/Chemical Name
sodium ((2-carboxylatophenyl)thio)(ethyl)mercury
InChi Key
RTKIYNMVFMVABJ-UHFFFAOYSA-L
InChi Code
InChI=1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2
SMILES Code
CC[Hg]Sc1c(C([O-])=O)cccc1.[Na+]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
|
Solvent |
mg/mL |
mM |
comments |
| Solubility |
| Soluble in DMSO |
0.0 |
100.00 |
|
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.
Preparing Stock Solutions
The following data is based on the
product
molecular weight
404.81
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Dórea JG. Low-dose Thimerosal (ethyl-mercury) is still used in infants` vaccines: Should we be concerned with this form of exposure? J Trace Elem Med Biol. 2018 Sep;49:134-139. doi: 10.1016/j.jtemb.2018.05.010. Epub 2018 May 17. PMID: 29895363.
2: Dórea JG, Farina M, Rocha JB. Toxicity of ethylmercury (and Thimerosal): a comparison with methylmercury. J Appl Toxicol. 2013 Aug;33(8):700-11. doi: 10.1002/jat.2855. Epub 2013 Feb 11. PMID: 23401210.
3: Hooker B, Kern J, Geier D, Haley B, Sykes L, King P, Geier M. Methodological issues and evidence of malfeasance in research purporting to show thimerosal in vaccines is safe. Biomed Res Int. 2014;2014:247218. doi: 10.1155/2014/247218. Epub 2014 Jun 4. PMID: 24995277; PMCID: PMC4065774.
4: Uno Y, Uchiyama T, Kurosawa M, Aleksic B, Ozaki N. Early exposure to the combined measles-mumps-rubella vaccine and thimerosal-containing vaccines and risk of autism spectrum disorder. Vaccine. 2015 May 15;33(21):2511-6. doi: 10.1016/j.vaccine.2014.12.036. Epub 2015 Jan 3. PMID: 25562790.
5: Peng B, Che D, Hao Y, Zheng Y, Liu R, Qian Y, Cao J, Wang J, Zhang Y, He L, Geng S. Thimerosal induces skin pseudo-allergic reaction via Mas-related G-protein coupled receptor B2. J Dermatol Sci. 2019 Sep;95(3):99-106. doi: 10.1016/j.jdermsci.2019.07.007. Epub 2019 Jul 24. PMID: 31558225.
6: Nelson KB, Bauman ML. Thimerosal and autism? Pediatrics. 2003 Mar;111(3):674-9. doi: 10.1542/peds.111.3.674. PMID: 12612255.
7: Dórea JG. Low-dose Thimerosal in pediatric vaccines: Adverse effects in perspective. Environ Res. 2017 Jan;152:280-293. doi: 10.1016/j.envres.2016.10.028. Epub 2016 Nov 3. PMID: 27816865.
8: Sykes LK, Geier DA, King PG, Kern JK, Haley BE, Chaigneau CG, Megson MN, Love JM, Reeves RE, Geier MR. Thimerosal as discrimination: vaccine disparity in the UN Minamata Convention on mercury. Indian J Med Ethics. 2014 Oct- Dec;11(4):206-18. doi: 10.20529/IJME.2014.054. Epub 2014 Apr 11. PMID: 25101548.
9: Geier DA, King PG, Hooker BS, Dórea JG, Kern JK, Sykes LK, Geier MR. Thimerosal: clinical, epidemiologic and biochemical studies. Clin Chim Acta. 2015 Apr 15;444:212-20. doi: 10.1016/j.cca.2015.02.030. Epub 2015 Feb 21. PMID: 25708367.
10: Mádi A. Being on the track of thimerosal. Review. Acta Microbiol Immunol Hung. 2005;52(1):95-103. doi: 10.1556/AMicr.52.2005.1.5. PMID: 15957237.
