MedKoo Cat#: 413227 | Name: Chlorcolchicine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Chlorcolchicine is a potent antimitotic agent in cultured fibroblasts and in the Ehrlich Lettre ascites tumor. It has been used for topical treatment of skin tumors

Chemical Structure

Chlorcolchicine
Chlorcolchicine
CAS#26279-89-0

Theoretical Analysis

MedKoo Cat#: 413227

Name: Chlorcolchicine

CAS#: 26279-89-0

Chemical Formula: C22H24ClNO6

Exact Mass: 433.1292

Molecular Weight: 433.89

Elemental Analysis: C, 60.90; H, 5.58; Cl, 8.17; N, 3.23; O, 22.12

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Chlorcolchicine; NSC142024; NSC-142024; NSC 142024
IUPAC/Chemical Name
Acetamide, 2-chloro-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)- (9CI)
InChi Key
XBFWCWRZDWNRIE-HNNXBMFYSA-N
InChi Code
InChI=1S/C22H24ClNO6/c1-27-17-8-6-13-14(10-16(17)25)15(24-19(26)11-23)7-5-12-9-18(28-2)21(29-3)22(30-4)20(12)13/h6,8-10,15H,5,7,11H2,1-4H3,(H,24,26)/t15-/m0/s1
SMILES Code
O=C(N[C@H](C1=C2)CCC3=CC(OC)=C(OC)C(OC)=C3C1=CC=C(OC)C2=O)CCl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 433.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Jung EG, Werner D. Chlorkolchizin zur lokalen Behandlung von Hauttumoren [Chlorcolchicine in the localized treatment of skin tumors]. Schweiz Med Wochenschr. 1974 Feb 23;104(8):265-8. German. PMID: 4814677.