MedKoo Cat#: 413156 | Name: Chlorbenzoxamine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Chlorbenzoxamine is a drug used for functional gastrointestinal disorders.

Chemical Structure

Chlorbenzoxamine
Chlorbenzoxamine
CAS#522-18-9

Theoretical Analysis

MedKoo Cat#: 413156

Name: Chlorbenzoxamine

CAS#: 522-18-9

Chemical Formula: C27H31ClN2O

Exact Mass: 434.2125

Molecular Weight: 435.01

Elemental Analysis: C, 74.55; H, 7.18; Cl, 8.15; N, 6.44; O, 3.68

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Chlorbenzoxamine; Clorbenzossamina; EINECS 208-323-0
IUPAC/Chemical Name
1-(2-((2-chlorophenyl)(phenyl)methoxy)ethyl)-4-(2-methylbenzyl)piperazine
InChi Key
VEVSKUJZSMGTMM-UHFFFAOYSA-N
InChi Code
InChI=1S/C27H31ClN2O/c1-22-9-5-6-12-24(22)21-30-17-15-29(16-18-30)19-20-31-27(23-10-3-2-4-11-23)25-13-7-8-14-26(25)28/h2-14,27H,15-21H2,1H3
SMILES Code
Cc1c(CN2CCN(CC2)CCOC(c3c(Cl)cccc3)c4ccccc4)cccc1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 435.01 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. [Clinical trials of chlorbenzoxamine]. CANDAELE N. Brux Med. 1959 Mar 1;39(9):301-18. PMID: 13629173 French. No abstract available. 2. [Study of the activity of chlorbenzoxamine in various types of experimental ulcers]. LEVIS S, BEERSAERTS J. Arch Int Pharmacodyn Ther. 1960 Jul 1;126:359-64. PMID: 14416321 French. No abstract available. 3. [RESULTS OF CLINICAL EXPERIENCES WITH CHLORBENZOXAMINE]. DELATORREFERNANDEZ J, GALANNAVARRO JL. Clin Lab (Zaragoza). 1964 Dec;78:413-6. PMID: 14256886 Spanish. No abstract available. 4. Screening procedure for the detection of alkanolamine antihistamines and their metabolites in urine using computerized gas chromatography-mass spectrometry. Maurer H, Pfleger K. J Chromatogr. 1988 Jun 24;428(1):43-60. doi: 10.1016/s0378-4347(00)83889-x. PMID: 2902103 5. The effect of chlorbenzoxamine upon symptoms and healing of peptic ulcer. Varis K, Nyberg O, Gorbatow O, Pörsti P, Aukee S, Perttala Y, Spoof M, Siurala M. Scand J Gastroenterol. 1972;7(6):547-9. doi: 10.3109/00365527209180954. PMID: 4564225 Clinical Trial. No abstract available. 6. Clinical experience with chlorbenzoxamine in the treatment of inflammation and edema. MILLER JM, GINSBERG M, JOHNSON HR, BOGOSIAN A. Antibiotic Med Clin Ther (New York). 1961 Jan;8:55-6. PMID: 13770828 No abstract available. 7. [Results obtained in the treatment of gastroduodenal ulcer by means of a medicinal agent with central action: chlorbenzoxamine]. GONZALEZ-LEPRAT JA. Brux Med. 1961 May 28;41:773-87. PMID: 13706960 French. No abstract available. 8. [Modifications of diencephalic reactivity to stimuli of various types induced by chlorbenzoxamine]. MALAMANI V, FEDELI S. Rass Neurol Veg. 1960 Oct 31;15:173-89. PMID: 14468788 Italian. No abstract available. 9. [Experimental and clinical research on the mechanism of action of chlorbenzoxamine]. ARCANGELI P. Rass Neurol Veg. 1960 Jun 30;15:121-30. PMID: 13862061 Italian. No abstract available. 10. [Attempts at treatment of duodenal ulcers with chlorbenzoxamine]. KANOUI F.