GR-112000 | CAS# 150351-90-9 | Biochemical

MedKoo Cat#: 575978 | Name: GR-112000

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GR-112000 is a peptide-based tachykinin NK2 receptor antagonist.

Chemical Structure

GR-112000

CAS#150351-90-9

Theoretical Analysis

MedKoo Cat#: 575978

Name: GR-112000

CAS#: 150351-90-9

Chemical Formula: C30H36N6O3

Exact Mass: 528.2849

Molecular Weight: 528.66

Elemental Analysis: C, 68.16; H, 6.86; N, 15.90; O, 9.08

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

GR 112,000; GR 112000; GR112000; GR-112000

IUPAC/Chemical Name

N-((S)-1-((R)-3-(1H-indol-3-yl)-2-(isopentyl(methyl)amino)propanamido)-1-oxopropan-2-yl)-2-phenyl-1H-imidazole-4-carboxamide

InChi Key

PGQAWGUJYNECHG-RXFWQSSRSA-N

InChi Code

InChI=1S/C30H36N6O3/c1-19(2)14-15-36(4)26(16-22-17-31-24-13-9-8-12-23(22)24)30(39)35-28(37)20(3)33-29(38)25-18-32-27(34-25)21-10-6-5-7-11-21/h5-13,17-20,26,31H,14-16H2,1-4H3,(H,32,34)(H,33,38)(H,35,37,39)/t20-,26+/m0/s1

SMILES Code

CC(C)CCN(C)[C@H](Cc1c[nH]c2ccccc12)C(=O)NC(=O)[C@H](C)NC(=O)c3c[nH]c(n3)c4ccccc4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 528.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Quartara L, Rovero P, Maggi CA. Peptide-based tachykinin NK2 receptor antagonists. Med Res Rev. 1995 Mar;15(2):139-55. doi: 10.1002/med.2610150205. PMID: 7537837.