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MedKoo Cat#: 463946 | Name: Thidiazuron
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Thidiazuron is a highly efficient bioregulator of plant morphogenesis in the tissue culture technique, inducing diverse responses ranging from induction of callus to embryogenesis or organogenesis, acting through modulation of the endogenous plant growth regulators, modification in cell membranes, energy levels, nutrient uptake, or nutrient assimilation.

Chemical Structure

Thidiazuron
Thidiazuron
CAS#51707-55-2

Theoretical Analysis

MedKoo Cat#: 463946

Name: Thidiazuron

CAS#: 51707-55-2

Chemical Formula: C9H8N4OS

Exact Mass: 220.0419

Molecular Weight: 220.25

Elemental Analysis: C, 49.08; H, 3.66; N, 25.44; O, 7.26; S, 14.56

Price and Availability

Size Price Availability Quantity
1g USD 350.00 2 Weeks
2g USD 550.00 2 Weeks
5g USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
Thidiazuron; TDZ; Defolit; Dropp;
IUPAC/Chemical Name
1-phenyl-3-(1,2,3-thiadiazol-5-yl)urea
InChi Key
HFCYZXMHUIHAQI-UHFFFAOYSA-N
InChi Code
InChI=1S/C9H8N4OS/c14-9(12-8-6-10-13-15-8)11-7-4-2-1-3-5-7/h1-6H,(H2,11,12,14)
SMILES Code
O=C(NC1=CN=NS1)NC2=CC=CC=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 220.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Khatri P, Joshee N. Somatic embryogenesis and shoot organogenesis in peanut cv. 'Georgia-12Y' and successful transfer to the soil. PLoS One. 2024 Dec 6;19(12):e0315060. doi: 10.1371/journal.pone.0315060. PMID: 39642150; PMCID: PMC11623556. 2: Chukwurah PN, Osuagwu AN, Fawibe OO, Ekerette EE. Development of an in vitro regeneration system for Heinsia crinita (Afz.) G. Taylor via direct induction of shoot proliferation from explants. BMC Res Notes. 2024 Nov 27;17(1):350. doi: 10.1186/s13104-024-07002-4. PMID: 39605102; PMCID: PMC11603656. 3: Hermosaningtyas AA, Totoń E, Lisiak N, Kruszka D, Budzianowska A, Kikowska M. Evaluation of Cytotoxic Activity of Cell Biomass from Eryngium planum and Lychnis flos-cuculi on Melanoma Cancer Cell. Molecules. 2024 Oct 31;29(21):5158. doi: 10.3390/molecules29215158. PMID: 39519799; PMCID: PMC11547748. 4: Zhou W, Yang G, Pan D, Wang X, Han Q, Qin Y, Li K, Huang G. Analysis of the plant hormone expression profile during somatic embryogenesis induction in teak (Tectona grandis). Front Plant Sci. 2024 Oct 7;15:1429575. doi: 10.3389/fpls.2024.1429575. PMID: 39439509; PMCID: PMC11494608. 5: Sorokin A, Kovalchuk I. Development of efficient and scalable regeneration tissue culture method for Cannabis sativa. Plant Sci. 2025 Jan;350:112296. doi: 10.1016/j.plantsci.2024.112296. Epub 2024 Oct 18. PMID: 39427697. 6: Azmi AF, Osman NI. Growth Promotion and In vitro Seed Germination of Lycium barbarum L. (Red Goji) Using Different Types of Cytokinins. Recent Adv Food Nutr Agric. 2024 Oct 8. doi: 10.2174/012772574X313421240902052600. Epub ahead of print. PMID: 39385425. 7: Chai LC, Alderson PG, Chin CF. Exogenous Cytokinin Induces Callus and Protocorm-Like-Bodies Formation in In Vitro Root Tips of Vanilla planifolia Andrews. Trop Life Sci Res. 2024 Mar;35(1):235-258. doi: 10.21315/tlsr2024.35.1.13. Epub 2024 Mar 30. PMID: 39262862; PMCID: PMC11383634. 8: Somtrakoon K, Chouychai W. Enhancing growth and phytoremediation efficiency of Pennisetum purpureum cv. Mahasarakham in weathered PAH-contaminated soil through thidiazuron application. Int J Phytoremediation. 2024;26(14):2336-2347. doi: 10.1080/15226514.2024.2389561. Epub 2024 Aug 15. PMID: 39145743. 9: Demidenko DV, Varlamova NV, Soboleva TM, Shitikova AV, Khaliluev MR. An Efficient and Rapid Protocol for Somatic Shoot Organogenesis from Juvenile Hypocotyl-Derived Callus of Castor Bean cv. Zanzibar Green. BioTech (Basel). 2024 Jul 4;13(3):25. doi: 10.3390/biotech13030025. PMID: 39051340; PMCID: PMC11270351. 10: Dong Y, Huang L, Liu J, Nong H, Li H, Zhang W, Zheng H, Tao J. Genome-wide identified VvOFP genes family and VvOFP4 functional characterization provide insight into fruit shape in grape. Int J Biol Macromol. 2024 Sep;276(Pt 1):133880. doi: 10.1016/j.ijbiomac.2024.133880. Epub 2024 Jul 17. PMID: 39025176. 11: Abdalla N, Dobránszki J. Meta-Topolin as an Effective Benzyladenine Derivative to Improve the Multiplication Rate and Quality of In Vitro Axillary Shoots of Húsvéti Rozmaring Apple Scion. Plants (Basel). 2024 Jun 6;13(11):1568. doi: 10.3390/plants13111568. PMID: 38891376; PMCID: PMC11174652. 12: Shu H, Sun S, Wang X, Chen J, Yang C, Zhang G, Han H, Li Z, Liang T, Liu R. Thidiazuron combined with cyclanilide modulates hormone pathways and ROS systems in cotton, increasing defoliation at low temperatures. Front Plant Sci. 2024 Apr 3;15:1333816. doi: 10.3389/fpls.2024.1333816. PMID: 38633458; PMCID: PMC11021790. 13: Akter F, Wu S, Islam MS, Kyaw H, Yang J, Li M, Fu Y, Wu J. An Efficient Agrobacterium-Mediated Genetic Transformation System for Gene Editing in Strawberry (Fragaria × ananassa). Plants (Basel). 2024 Feb 20;13(5):563. doi: 10.3390/plants13050563. PMID: 38475410; PMCID: PMC10934387. 14: Zamani M, Sonboli A, Goldansaz M, Mirjalili MH. In vitro micropropagation and conservation of endangered medicinal plant Nepeta asterotricha Rech.f. (Lamiaceae): genetic fidelity, phytochemical and biological assessment. Physiol Mol Biol Plants. 2024 Jan;30(1):67-80. doi: 10.1007/s12298-024-01416-x. Epub 2024 Feb 23. PMID: 38435858; PMCID: PMC10901756. 15: Xue Y, Hiti-Bandaralage JCA, Hu Z, Zhao Z, Mitter N. First Report on Mesophyll Protoplast Isolation and Regeneration System for the Duboisia Species. Plants (Basel). 2023 Dec 21;13(1):40. doi: 10.3390/plants13010040. PMID: 38202348; PMCID: PMC10780843. 16: Ma Y, Pan Y, Mao B. Regenerating Saffron (Crocus sativus L.) from Corm Lateral Buds via Indirect Somatic Embryogenesis. Plants (Basel). 2023 Dec 19;13(1):10. doi: 10.3390/plants13010010. PMID: 38202318; PMCID: PMC10780922. 17: Wang J, Cai X, Zeng S, Zhang Z, Chi Q, Guo W. Effect of forchlorfenuron and thidiazuron on kiwifruits' internal qualities, optical properties and their relationship during growth. Spectrochim Acta A Mol Biomol Spectrosc. 2024 Mar 5;308:123749. doi: 10.1016/j.saa.2023.123749. Epub 2023 Dec 10. PMID: 38113558. 18: Song W, Song Y, Liu X, Zhang X, Xin R, Duan S, Guan S, Sun X. Improvement of Culture Conditions and Plant Growth Regulators for In Vitro Callus Induction and Plant Regeneration in Paeonia lactiflora Pall. Plants (Basel). 2023 Nov 25;12(23):3968. doi: 10.3390/plants12233968. PMID: 38068606; PMCID: PMC10707782. 19: Cortés-Olmos C, Guerra-Sandoval VM, Blanca-Giménez V, Rodríguez-Burruezo A. Micropropagation and Acclimatization of Gymnocalycium cv. Fancy (Cactaceae): Developmental Responses to Different Explant Types and Hormone Conditions. Plants (Basel). 2023 Nov 22;12(23):3932. doi: 10.3390/plants12233932. PMID: 38068570; PMCID: PMC10708245. 20: Yu S, Zehra A, Sahito ZA, Wang W, Chen S, Feng Y, He Z, Yang X. Cytokinin- mediated shoot proliferation and its correlation with phytoremediation effects in Cd-hyperaccumulator ecotype of Sedum alfredii. Sci Total Environ. 2024 Feb 20;912:168993. doi: 10.1016/j.scitotenv.2023.168993. Epub 2023 Dec 2. PMID: 38043818.