MedKoo Cat#: 575960 | Name: Fluparoxan

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fluparoxan is a highly selective alpha2-adrenoceptor antagonist.

Chemical Structure

Fluparoxan
Fluparoxan
CAS#105182-45-4

Theoretical Analysis

MedKoo Cat#: 575960

Name: Fluparoxan

CAS#: 105182-45-4

Chemical Formula: C10H10FNO2

Exact Mass: 195.0696

Molecular Weight: 195.19

Elemental Analysis: C, 61.53; H, 5.16; F, 9.73; N, 7.18; O, 16.39

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Fluparoxan; GR 50360; GR50360; GR-50360; GR 50360A; GR50360A; GR-50360A
IUPAC/Chemical Name
1H-(1,4)Benzodioxino(2,3-c)pyrrole, 5-fluoro-2,3,3a,9a-tetrahydro-, (3aS-trans)-
InChi Key
XSOUHEXVEOQRKJ-IUCAKERBSA-N
InChi Code
InChI=1S/C10H10FNO2/c11-6-2-1-3-7-10(6)14-9-5-12-4-8(9)13-7/h1-3,8-9,12H,4-5H2/t8-,9-/m0/s1
SMILES Code
Fc1cccc2O[C@H]3CNC[C@@H]3Oc12
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 195.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Borthwick AD. Fluparoxan: A Comprehensive Review of its Discovery, Adrenergic and CNS Activity and Treatment of Cognitive Dysfunction in Central Neurodegenerative Diseases. Mini Rev Med Chem. 2017;17(7):572-582. doi: 10.2174/1389557516666160321115041. PMID: 26996616. 2. Halliday CA, Jones BJ, Skingle M, Walsh DM, Wise H, Tyers MB. The pharmacology of fluparoxan: a selective alpha 2-adrenoceptor antagonist. Br J Pharmacol. 1991 Apr;102(4):887-95. doi: 10.1111/j.1476-5381.1991.tb12272.x. PMID: 1677298; PMCID: PMC1917968.