Rigin | CAS# 77727-17-4 | Tetrapeptide

MedKoo Cat#: 575956 | Name: Rigin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Rigin is a Tuftsin-like tetrapeptide with equal phagocytosis stimulating activity.

Chemical Structure

Rigin

CAS#77727-17-4

Theoretical Analysis

MedKoo Cat#: 575956

Name: Rigin

CAS#: 77727-17-4

Chemical Formula: C18H32N8O6

Exact Mass: 456.2445

Molecular Weight: 456.50

Elemental Analysis: C, 47.36; H, 7.07; N, 24.55; O, 21.03

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Gly-gln-pro-arg; GQPR; Rigin; Tetrapeptide-3; Tetrapeptide-7

IUPAC/Chemical Name

L-Arginine, N2-(1-(N2-glycyl-L-glutaminyl)-L-prolyl)-

InChi Key

UEJYSALTSUZXFV-SRVKXCTJSA-N

InChi Code

InChI=1S/C18H32N8O6/c19-9-14(28)24-10(5-6-13(20)27)16(30)26-8-2-4-12(26)15(29)25-11(17(31)32)3-1-7-23-18(21)22/h10-12H,1-9,19H2,(H2,20,27)(H,24,28)(H,25,29)(H,31,32)(H4,21,22,23)/t10-,11-,12-/m0/s1

SMILES Code

NCC(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 456.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Dutta RC, Puri A, Anand N. Immunomodulatory potential of hydrophobic analogs of Rigin and their role in providing protection against Plasmodium berghei infection in mice. Int Immunopharmacol. 2001 May;1(5):843-55. doi: 10.1016/s1567-5769(01)00021-2. PMID: 11379040. 2. Veretennikova NI, Chipens GI, Nikiforovich GV, Betinsh YR. Rigin, another phagocytosis-stimulating tetrapeptide isolated from human IgG. Confirmations of a hypothesis. Int J Pept Protein Res. 1981 Apr;17(4):430-5. doi: 10.1111/j.1399-3011.1981.tb02011.x. PMID: 7309346.