GM-237354 | CAS# 199013-04-2 | Antifungal

MedKoo Cat#: 575926 | Name: GM-237354

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GM-237354 is a sordarin derivative with antifungal activity.

Chemical Structure

GM-237354

CAS#199013-04-2

Theoretical Analysis

MedKoo Cat#: 575926

Name: GM-237354

CAS#: 199013-04-2

Chemical Formula: C29H40O6

Exact Mass: 484.2825

Molecular Weight: 484.63

Elemental Analysis: C, 71.87; H, 8.32; O, 19.81

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

GM237354; GM 237354; GM-237354

IUPAC/Chemical Name

(1S,3aR,4S,4aR,7R,7aR,8aS)-4-formyl-3-isopropyl-7-methyl-8a-((((3aR,5R,7R,7aS)-7-methyl-3-methylenehexahydro-2H-furo[2,3-c]pyran-5-yl)oxy)methyl)-4,4a,5,6,7,7a,8,8a-octahydro-1,4-methano-s-indacene-3a(1H)-carboxylic acid

InChi Key

GGMPSVPIOWGTTA-JZHLRACDSA-N

InChi Code

InChI=1S/C29H40O6/c1-15(2)23-8-19-10-27(13-30)22-7-6-16(3)21(22)11-28(19,29(23,27)26(31)32)14-34-24-9-20-17(4)12-33-25(20)18(5)35-24/h8,13,15-16,18-22,24-25H,4,6-7,9-12,14H2,1-3,5H3,(H,31,32)/t16-,18-,19-,20-,21-,22-,24-,25-,27+,28+,29+/m1/s1

SMILES Code

CC(C)C1=C[C@@H]2C[C@]3(C=O)[C@@H]4CC[C@@H](C)[C@H]4C[C@@]2(CO[C@H]5C[C@H]6[C@H](OCC6=C)[C@@H](C)O5)[C@]13C(=O)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 484.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Herreros E, Martinez CM, Almela MJ, Marriott MS, De Las Heras FG, Gargallo-Viola D. Sordarins: in vitro activities of new antifungal derivatives against pathogenic yeasts, Pneumocystis carinii, and filamentous fungi. Antimicrob Agents Chemother. 1998 Nov;42(11):2863-9. doi: 10.1128/AAC.42.11.2863. PMID: 9797217; PMCID: PMC105957.