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MedKoo Cat#: 463939 | Name: Nitrofurantoin sodium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nitrofurantoin Sodium is a sodium salt form of nitrofurantoin, a synthetic derivative of imidazolidinedione (hydantoin) that inhibits bacterial DNA, RNA, and cell wall protein synthesis.

Chemical Structure

Nitrofurantoin sodium
CAS#54-87-5 (sodium)

Theoretical Analysis

MedKoo Cat#: 463939

Name: Nitrofurantoin sodium

CAS#: 54-87-5 (sodium)

Chemical Formula: C8H5N4NaO5

Exact Mass:

Molecular Weight: 260.14

Elemental Analysis: C, 36.94; H, 1.94; N, 21.54; Na, 8.84; O, 30.75

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Nitrofurantoin sodium; Ivadantin; Sodium nitrofurantoin;
IUPAC/Chemical Name
sodium (E)-3-(((5-nitrofuran-2-yl)methylene)amino)-2,5-dioxoimidazolidin-1-ide
InChi Key
AFDJQFFKYDCYIG-JSGFVSQVSA-M
InChi Code
InChI=1S/C8H6N4O5.Na/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16;/h1-3H,4H2,(H,10,13,14);/q;+1/p-1/b9-3+;
SMILES Code
[O-][N+](c1ccc(/C=N/N2CC([N-]C2=O)=O)o1)=O.[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 260.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Daoud N, Hamdoun M, Hannachi H, Gharsallah C, Mallekh W, Bahri O. Antimicrobial Susceptibility Patterns of Escherichia coli among Tunisian Outpatients with Community-Acquired Urinary Tract Infection (2012-2018). Curr Urol. 2020 Dec;14(4):200-205. doi: 10.1159/000499238. Epub 2020 Dec 18. PMID: 33488338; PMCID: PMC7810217. 2: Babu B, Sathiyaraj G, Mandal A, Kandan S, Biju N, Palanisamy S, You S, Girijakumari Nisha R, Marimuthu Prabhu N. Surveillance of disease incidence in shrimp farms located in the east coastal region of India and in vitro antibacterial efficacy of probiotics against Vibrio parahaemolyticus. J Invertebr Pathol. 2021 Jan 17:107536. doi: 10.1016/j.jip.2021.107536. Epub ahead of print. PMID: 33472086. 3: Tula A, Mikru A, Alemayehu T, Dobo B. Bacterial Profile and Antibiotic Susceptibility Pattern of Urinary Tract Infection among Pregnant Women Attending Antenatal Care at a Tertiary Care Hospital in Southern Ethiopia. Can J Infect Dis Med Microbiol. 2020 Dec 24;2020:5321276. doi: 10.1155/2020/5321276. PMID: 33425076; PMCID: PMC7775162. 4: Samancı S, Çelik M, Köşker M. Antibiotic resistance in childhood urinary tract infections: A single-center experience. Turk Pediatri Ars. 2020 Dec 16;55(4):386-392. doi: 10.14744/TurkPediatriArs.2020.22309. PMID: 33414656; PMCID: PMC7750337. 5: Zhong ZX, Cui ZH, Li XJ, Tang T, Zheng ZJ, Ni WN, Fang LX, Zhou YF, Yu Y, Liu YH, Liao XP, Sun J. Nitrofurantoin Combined With Amikacin: A Promising Alternative Strategy for Combating MDR Uropathogenic Escherichia coli. Front Cell Infect Microbiol. 2020 Dec 21;10:608547. doi: 10.3389/fcimb.2020.608547. PMID: 33409159; PMCID: PMC7779487. 6: Eshetea BB, Addy N, Ewing L, Beaubrun JJ, Eribo B. Antibiotic Resistance Characteristics and Prevalence in Kitfo, an Ethiopian Beef Tartar. J Food Prot. 2021 Jan 1;84(1):152-159. doi: 10.4315/JFP-20-230. PMID: 33411928. 7: Balamurugan M, Alagumalai K, Chen TW, Chen SM, Liu X, Selvaganapathy M. Simultaneous electrochemical determination of nitrofurantoin and nifedipine with assistance of needle-shaped perovskite structure: barium stannate fabricated glassy carbon electrode. Mikrochim Acta. 2021 Jan 6;188(1):19. doi: 10.1007/s00604-020-04645-5. PMID: 33404774. 8: Zhu NJ, McLeod M, McNulty CAM, Lecky DM, Holmes AH, Ahmad R. Trends in Antibiotic Prescribing in Out-of-Hours Primary Care in England from January 2016 to June 2020 to Understand Behaviours during the First Wave of COVID-19. Antibiotics (Basel). 2021 Jan 1;10(1):32. doi: 10.3390/antibiotics10010032. PMID: 33401408; PMCID: PMC7824631. 9: Quino W, Hurtado CV, Meza AM, Zamudio ML, Gavilan RG. Patrones de resistencia a los antimicrobianos en serovares de Salmonella enterica en Perú, 2012-2015 [Patterns of resistance to antimicrobials in serovars of Salmonella enterica in Peru, 2012-2015]. Rev Chilena Infectol. 2020 Aug;37(4):395-401. Spanish. doi: 10.4067/S0716-10182020000400395. PMID: 33399660. 10: Boriollo MFG, Moreira BS, Oliveira MC, Santos TO, Rufino LRA, Oliveira NMS. Incidence of Shiga toxin-producing Escherichia coli in diarrheic calves and its susceptibility profile to antimicrobials and Eugenia uniflora L. Can J Vet Res. 2021 Jan;85(1):18-26. PMID: 33390649; PMCID: PMC7747658. 11: Eissa F, Ghanem K, Al-Sisi M. Occurrence and human health risks of pesticides and antibiotics in Nile tilapia along the Rosetta Nile branch, Egypt. Toxicol Rep. 2020 Mar 20;7:1640-1646. doi: 10.1016/j.toxrep.2020.03.004. PMID: 33384941; PMCID: PMC7772442. 12: Ochoa SA, Cruz-Córdova A, Mancilla-Rojano J, Escalona-Venegas G, Esteban- Kenel V, Franco-Hernández I, Parra-Ortega I, Arellano-Galindo J, Hernández- Castro R, Perez-López CF, De la Rosa-Zamboni D, Xicohtencatl-Cortes J. Control of Methicillin-Resistant Staphylococcus aureus Strains Associated With a Hospital Outbreak Involving Contamination From Anesthesia Equipment Using UV-C. Front Microbiol. 2020 Dec 14;11:600093. doi: 10.3389/fmicb.2020.600093. PMID: 33381094; PMCID: PMC7767929. 13: Egbule OS, Iweriebor BC, Odum EI. Beta-Lactamase-Producing Escherichia coli Isolates Recovered from Pig Handlers in Retail Shops and Abattoirs in Selected Localities in Southern Nigeria: Implications for Public Health. Antibiotics (Basel). 2020 Dec 24;10(1):9. doi: 10.3390/antibiotics10010009. PMID: 33374204; PMCID: PMC7824224. 14: Kim S, Cheng KC, Patell S, Alsikafi NF, Breyer BN, Broghammer JA, Elliott SP, Erickson BA, Myers JB, Smith TG 3rd, Vanni AJ, Voelzke BB, Zhao LC, Buckley JC. Antibiotic Stewardship and Postoperative Infections in Urethroplasties. Urology. 2020 Dec 26:S0090-4295(20)31517-X. doi: 10.1016/j.urology.2020.10.065. Epub ahead of print. PMID: 33373707. 15: Mehrabi M, Salehi B, Rassi H, Dehghan A. Evaluating the antibiotic resistance and frequency of adhesion markers among Escherichia coli isolated from type 2 diabetes patients with urinary tract infection and its association with common polymorphism of mannose-binding lectin gene. New Microbes New Infect. 2020 Nov 26;38:100827. doi: 10.1016/j.nmni.2020.100827. PMID: 33364032; PMCID: PMC7750139. 16: Aedo SJ, Tang J, Brynildsen MP. Metabolites potentiate nitrofurans in non- growing Escherichia coli. Antimicrob Agents Chemother. 2020 Dec 23:AAC.00858-20. doi: 10.1128/AAC.00858-20. Epub ahead of print. PMID: 33361301. 17: Ali G, Riaz-Ul-Hassan S, Shah MA, Javid MQ, Khan AR, Shakir L. Antibiotic susceptibility and drug prescription pattern in uropathogenic Escherichia coli in district Muzaffarabad, Azad Jammu and Kashmir, Pakistan. J Pak Med Assoc. 2020 Nov;70(11):2039-2042. doi: 10.5455/JPMA.10831. PMID: 33341855. 18: Soudais B, Lacroix-Hugues V, Meunier F, Gillibert A, Darmon D, Schuers M. Diagnosis and management of male urinary tract infections: a need for new guidelines. Study from a French general practice electronic database. Fam Pract. 2020 Dec 19:cmaa136. doi: 10.1093/fampra/cmaa136. Epub ahead of print. PMID: 33340317. 19: Ten Oever J. Nitrofurantoïne voor urineweginfecties bij mannen? [Nitrofurantoin for urinary tract infections in men: it is possible]. Ned Tijdschr Geneeskd. 2020 Oct 8;164:D5235. Dutch. PMID: 33331735. 20: Veillette JJ, Waters CD, Gelman SS, Hoopes L, Vargyas G, McKay A, Good T, Olson J, Vento TJ. Antibiotic prescribing for adult bacteriuria and pyuria in community hospital emergency departments. Am J Emerg Med. 2020 Dec 4;40:1-5. doi: 10.1016/j.ajem.2020.11.075. Epub ahead of print. PMID: 33326910.