MedKoo Cat#: 413114 | Name: Cloforex

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cloforex is an anorectic of the amphetamine class. It is a prodrug to chlorphentermine.

Chemical Structure

Cloforex
Cloforex
CAS#14261-75-7

Theoretical Analysis

MedKoo Cat#: 413114

Name: Cloforex

CAS#: 14261-75-7

Chemical Formula: C13H18ClNO2

Exact Mass: 255.1026

Molecular Weight: 255.74

Elemental Analysis: C, 61.05; H, 7.09; Cl, 13.86; N, 5.48; O, 12.51

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Cloforex; D237; D-237; D 237
IUPAC/Chemical Name
Ethyl (p-chloro-alpha,alpha-dimethylphenethyl)carbamate
InChi Key
TZWKUQDQKPYNLL-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H18ClNO2/c1-4-17-12(16)15-13(2,3)9-10-5-7-11(14)8-6-10/h5-8H,4,9H2,1-3H3,(H,15,16)
SMILES Code
O=C(OCC)NC(C)(C)CC1=CC=C(Cl)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 255.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Oberex (Draco) cloforex [Oberex (Draco) cloforex]. Lakartidningen. 1968 Mar 18;65:Suppl I:26. Swedish. PMID: 5743114. 2: Magnusson G, Magnusson O. Cloforex-induced pulmonary changes in rats. Beitr Pathol. 1972 Apr;146(1):79-88. PMID: 5050908. 3: Ryrfeldt A. The distribution, elimination, and biotransformation of 14C-cloforex in the mouse and rat. Acta Pharmacol Toxicol (Copenh). 1970;28(5):391-405. doi: 10.1111/j.1600-0773.1970.tb00565.x. PMID: 5536739. 4: Flodh H, Magnusson G. Genesis of foam cells: study in rats after administration of Cloforex. Virchows Arch B Cell Pathol. 1973 Mar 30;12(4):360-6. doi: 10.1007/BF02894012. PMID: 4350410. 5: Ryrfeldt A, Ramsay CH, Appelgren LE. The distribution and fate of 14C-cloforex in the lung of the rat. Acta Pharmacol Toxicol (Copenh). 1973;33(4):317-20. doi: 10.1111/j.1600-0773.1973.tb01532.x. PMID: 4800678. 6: Woodward SC. Induction and reversal of pulmonary lipid histiocytosis in rats following oral administration of anorectics cloforex and chlorphentermine. J Toxicol Environ Health. 1981 Mar-Apr;7(3-4):569-83. doi: 10.1080/15287398109530002. PMID: 7197305. 7: Bülow M, Dell HD, Fiedler J, Kamp R, Lorenz D. Stoffwechsel und Verteilung von Chlorphentermin und Cloforex bei Tier und Mesch [Metabolism and distribution of chlorphentermine and clorofex in animal and man]. Arzneimittelforschung. 1971 Jan;21(1):86-93. German. PMID: 5108205.