Guaifenesin-d3 | CAS#1189924-85-3 | Guaifenesin quantification internal standard

MedKoo Cat#: 463920 | Name: Guaifenesin-d3

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Guaifenesin-d3 is intended for use as an internal standard for the quantification of guaifenesin by GC- or LC-MS. Guaifenesin is an expectorant. It inhibits production of mucin 5AC (MUC5AC), reduces mucus viscosity and elasticity, and increases the mucociliary transport rate of endogenous particles in primary human tracheobronchial epithelial cells in a concentration-dependent manner. Guaifenesin increases phenol red secretion, a marker of expectorant activity, in rats.3 Formulations containing guaifenesin have been used as expectorants in the treatment of the common cold and chronic bronchitis.

Chemical Structure

Guaifenesin-d3

CAS#1189924-85-3

Theoretical Analysis

MedKoo Cat#: 463920

Name: Guaifenesin-d3

CAS#: 1189924-85-3

Chemical Formula: C10H11D3O4

Exact Mass: 201.1080

Molecular Weight: 201.24

Elemental Analysis: C, 59.69; H, 8.51; O, 31.80

Price and Availability

Size	Price	Availability	Quantity
1mg	USD 350.00	2 Weeks
5mg	USD 750.00	2 Weeks

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Related CAS #

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Synonym

Guaifenesin-d3; Guaifenesin d3; MY-301-d3; MY301 d3; MY-301 d3; MY301-d3; SL90-d3; SL 90-d3; SL-90-d3; SL90-d3; SL 90 d3; SL-90-d3; XL90-d3; XL 90-d3; XL-90-d3; XL90 d3; XL 90 d3; XL-90 d3;

IUPAC/Chemical Name

3-(2-(methoxy-d3)phenoxy)propane-1,2-diol

InChi Key

HSRJKNPTNIJEKV-FIBGUPNXSA-N

InChi Code

InChI=1S/C10H14O4/c1-13-9-4-2-3-5-10(9)14-7-8(12)6-11/h2-5,8,11-12H,6-7H2,1H3/i1D3

SMILES Code

OCC(COC1=C(OC([2H])([2H])[2H])C=CC=C1)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Product Data

Product Data

Instruction

View handling instruction

Biological target:

Guaifenesin-d3 (Guaiacol glyceryl ether-d3) is the deuterium labeled Guaifenesin.

In vitro activity:

TBD

In vivo activity:

TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 201.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

TBD

In vitro protocol:

TBD

In vivo protocol:

TBD

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