Gliflumide | CAS# 35253-24-8 | Biochemical

MedKoo Cat#: 575897 | Name: Gliflumide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Gliflumide is an antidiabetic.

Chemical Structure

Gliflumide

CAS#35253-24-8

Theoretical Analysis

MedKoo Cat#: 575897

Name: Gliflumide

CAS#: 35253-24-8

Chemical Formula: C25H29FN4O4S

Exact Mass: 500.1894

Molecular Weight: 500.59

Elemental Analysis: C, 59.98; H, 5.84; F, 3.80; N, 11.19; O, 12.78; S, 6.40

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Gliflumide; ZK 28200; ZK28200; ZK-28200

IUPAC/Chemical Name

n-(1-(5-fluoro-2-methoxyphenyl)ethyl)-4-(((5-(2-methylpropyl)-2-pyrimidinyl)amino)sulfonyl)benzeneacetamide

InChi Key

CKOLETHYECDWSS-UHFFFAOYSA-N

InChi Code

InChI=1S/C25H29FN4O4S/c1-16(2)11-19-14-27-25(28-15-19)30-35(32,33)21-8-5-18(6-9-21)12-24(31)29-17(3)22-13-20(26)7-10-23(22)34-4/h5-10,13-17H,11-12H2,1-4H3,(H,29,31)(H,27,28,30)

SMILES Code

COc1ccc(F)cc1C(C)NC(=O)Cc2ccc(cc2)S(=O)(=O)Nc3ncc(CC(C)C)cn3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 500.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Blumenbach L, Gerhards E, Gutsche H, Klein W, Loge O, Losert W, Schillinger E, Speck U, Vetter H, Wendt H. Gliflumide, a new oral antidiabetic of high potency and efficacy. Int J Clin Pharmacol Biopharm. 1975 Jul;12(1-2):141-51. PMID: 809367. 2. Schillinger E, Ehrenberg I, Lübke K. Stereospecific plasma binding of gliflumide, a new antidiabetic drug. Biochem Pharmacol. 1978 Mar 1;27(5):651-3. doi: 10.1016/0006-2952(78)90500-2. PMID: 566105.